Gene

dlx2a

ID
ZDB-GENE-980526-212
Name
distal-less homeobox 2a
Symbol
dlx2a Nomenclature History
Previous Names
  • dlx-2
  • dlx2
  • zgc:110518
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including neural crest cell development; pharyngeal system development; and skeletal system development. Predicted to localize to nuclear chromatin. Is expressed in several structures, including brain; cranial cartilage; neural crest; pectoral fin bud; and pharyngeal arch. Orthologous to human DLX2 (distal-less homeobox 2).
Genome Resources
Note
None
Expression
All Expression Data
380 figures from 261 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Sperber et al., 2008
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dlx2a Human Ortholog
No data available
Associated With dlx2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR000047 Helix-turn-helix motif
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR020479 Homeobox domain, metazoa
Domain IPR022135 Distal-less-like homeobox protein, N-terminal domain
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Distal-less-like homeobox protein, N-terminal domain Helix-turn-helix motif Homeobox, conserved site Homeobox domain Homeobox domain, metazoa Homeobox-like domain superfamily
UniProtKB:F6NKE2 274
UniProtKB:P50574 270
UniProtKB:Q503J7 271
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations