Morpholino

MO1-klf8

ID
ZDB-MRPHLNO-150928-3
Name
MO1-klf8
Previous Names
  • klf8-MO1 ATG (1)
Target
Sequence
5' - GTGCATCTCGGTATCTAAGCGGCGG - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
Translation-blocking MO.
Genome Resources
None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO1-klf8
Expressed Gene Anatomy Figures
atoh1a Fig. 6 with image from Tsai et al., 2015
cdkn1a Fig. 9 with image from Tsai et al., 2015
gata6 Fig. 1 with image from Lin et al., 2017
lft1 Fig. 2 with image from Lin et al., 2017
lft2 Fig. 2 with image from Lin et al., 2017
met Fig. 8 with image,  Fig. 9 with image,  Fig. S7 with image from Tsai et al., 2015
myl7 Fig. 1 with image from Lin et al., 2017
pitx2 Fig. 2 with image from Lin et al., 2017
ptf1a Fig. 4 with image from Tsai et al., 2015
reln Fig. 6 with image from Tsai et al., 2015
roraa Fig. 4 with image,  Fig. 5 with image from Tsai et al., 2015
spaw Fig. 2 with image,  Fig. 3 with image from Lin et al., 2017
tp53 Fig. 2 with image,  Fig. 9 with image from Tsai et al., 2015
Phenotype
Phenotype resulting from MO1-klf8
Phenotype Fish Figures
anterior lateral plate mesoderm spaw expression absent, abnormal AB + MO1-klf8 Fig. 2 with image from Lin et al., 2017
cerebellar granule cell decreased amount, abnormal WT + MO1-klf8 Fig. 6 with image from Tsai et al., 2015
cerebellar Purkinje cell differentiation disrupted, abnormal WT + MO1-klf8 Fig. 5 with image from Tsai et al., 2015
cerebellum morphology, abnormal WT + MO1-klf8 Fig. 1 with image from Tsai et al., 2015
cerebellum apoptotic process increased occurrence, abnormal WT + MO1-klf8 Fig. 3 with image from Tsai et al., 2015
cerebellum cell proliferation in hindbrain decreased occurrence, abnormal WT + MO1-klf8 Fig. 3 with image from Tsai et al., 2015
cerebellum development disrupted, abnormal WT + MO1-klf8 Fig. 1 with image,  Fig. 6 with image from Tsai et al., 2015
determination of intestine left/right asymmetry arrested, abnormal AB + MO1-klf8 Fig. 1 with image from Lin et al., 2017
determination of intestine left/right asymmetry process quality, abnormal AB + MO1-klf8 Fig. 1 with image from Lin et al., 2017
diencephalon left side lft1 expression absent, abnormal AB + MO1-klf8 Fig. 2 with image from Lin et al., 2017
eye decreased size, abnormal WT + MO1-klf8 Fig. 1 with image from Tsai et al., 2015
heart morphology, abnormal AB + MO1-klf8 Fig. 1 with image from Lin et al., 2017
heart jogging arrested, abnormal AB + MO1-klf8 Fig. 1 with image from Lin et al., 2017
heart jogging process quality, abnormal AB + MO1-klf8 Fig. 1 with image from Lin et al., 2017
heart looping arrested, abnormal AB + MO1-klf8 Fig. 1 with image from Lin et al., 2017
heart looping process quality, abnormal AB + MO1-klf8 Fig. 1 with image from Lin et al., 2017
heart rudiment lft1 expression absent, abnormal AB + MO1-klf8 Fig. 2 with image from Lin et al., 2017
heart rudiment lft2 expression absent, abnormal AB + MO1-klf8 Fig. 2 with image from Lin et al., 2017
heart tube displaced to whole organism right side, abnormal AB + MO1-klf8 Fig. 1 with image from Lin et al., 2017
heart tube medial orientation, abnormal AB + MO1-klf8 Fig. 1 with image from Lin et al., 2017
Kupffer's vesicle cilium decreased amount, abnormal s870Tg + MO1-klf8 Fig. 5 with image from Lin et al., 2017
Kupffer's vesicle cilium decreased length, abnormal s870Tg + MO1-klf8 Fig. 5 with image from Lin et al., 2017
lateral plate mesoderm spaw expression absent, abnormal AB + MO1-klf8 Fig. 2 with image from Lin et al., 2017
lateral plate mesoderm spaw expression decreased amount, abnormal AB + MO1-klf8 Fig. 2 with image from Lin et al., 2017
lateral plate mesoderm left side pitx2 expression absent, abnormal AB + MO1-klf8 Fig. 2 with image from Lin et al., 2017
lateral plate mesoderm left side spaw expression absent, abnormal AB + MO1-klf8 Fig. 3 with image from Lin et al., 2017
lateral plate mesoderm left side spaw expression decreased amount, abnormal AB + MO1-klf8 Fig. 2 with image from Lin et al., 2017
liver aplastic, abnormal AB + MO1-klf8 Fig. 1 with image from Lin et al., 2017
liver bilateral, abnormal AB + MO1-klf8 Fig. 1 with image from Lin et al., 2017
liver mislocalised, abnormal AB + MO1-klf8 Fig. 1 with image from Lin et al., 2017
pancreas aplastic, abnormal AB + MO1-klf8 Fig. 1 with image from Lin et al., 2017
pancreas bilateral, abnormal AB + MO1-klf8 Fig. 1 with image from Lin et al., 2017
pancreas mislocalised, abnormal AB + MO1-klf8 Fig. 1 with image from Lin et al., 2017
posterior lateral plate mesoderm spaw expression decreased amount, abnormal AB + MO1-klf8 Fig. 2 with image from Lin et al., 2017
whole organism has fewer parts of type forerunner cell group, abnormal s870Tg + MO1-klf8 Fig. 5 with image from Lin et al., 2017
Phenotype of all Fish created by or utilizing MO1-klf8
Phenotype Fish Conditions Figures
heart tube medial orientation, abnormal AB + MO1-klf8 standard conditions Fig. 1 with image from Lin et al., 2017
heart tube displaced to whole organism right side, abnormal AB + MO1-klf8 standard conditions Fig. 1 with image from Lin et al., 2017
determination of intestine left/right asymmetry process quality, abnormal AB + MO1-klf8 standard conditions Fig. 1 with image from Lin et al., 2017
lateral plate mesoderm left side spaw expression absent, abnormal AB + MO1-klf8 standard conditions Fig. 3 with image from Lin et al., 2017
lateral plate mesoderm left side spaw expression decreased amount, abnormal AB + MO1-klf8 standard conditions Fig. 2 with image from Lin et al., 2017
liver mislocalised, abnormal AB + MO1-klf8 standard conditions Fig. 1 with image from Lin et al., 2017
heart jogging process quality, abnormal AB + MO1-klf8 standard conditions Fig. 1 with image from Lin et al., 2017
liver bilateral, abnormal AB + MO1-klf8 standard conditions Fig. 1 with image from Lin et al., 2017
lateral plate mesoderm left side pitx2 expression absent, abnormal AB + MO1-klf8 standard conditions Fig. 2 with image from Lin et al., 2017
anterior lateral plate mesoderm spaw expression absent, abnormal AB + MO1-klf8 standard conditions Fig. 2 with image from Lin et al., 2017
heart rudiment lft2 expression absent, abnormal AB + MO1-klf8 standard conditions Fig. 2 with image from Lin et al., 2017
pancreas aplastic, abnormal AB + MO1-klf8 standard conditions Fig. 1 with image from Lin et al., 2017
determination of intestine left/right asymmetry arrested, abnormal AB + MO1-klf8 standard conditions Fig. 1 with image from Lin et al., 2017
lateral plate mesoderm spaw expression absent, abnormal AB + MO1-klf8 standard conditions Fig. 2 with image from Lin et al., 2017
heart looping arrested, abnormal AB + MO1-klf8 standard conditions Fig. 1 with image from Lin et al., 2017
heart jogging arrested, abnormal AB + MO1-klf8 standard conditions Fig. 1 with image from Lin et al., 2017
heart looping process quality, abnormal AB + MO1-klf8 standard conditions Fig. 1 with image from Lin et al., 2017
posterior lateral plate mesoderm spaw expression decreased amount, abnormal AB + MO1-klf8 standard conditions Fig. 2 with image from Lin et al., 2017
pancreas mislocalised, abnormal AB + MO1-klf8 standard conditions Fig. 1 with image from Lin et al., 2017
heart rudiment lft1 expression absent, abnormal AB + MO1-klf8 standard conditions Fig. 2 with image from Lin et al., 2017
diencephalon left side lft1 expression absent, abnormal AB + MO1-klf8 standard conditions Fig. 2 with image from Lin et al., 2017
lateral plate mesoderm spaw expression decreased amount, abnormal AB + MO1-klf8 standard conditions Fig. 2 with image from Lin et al., 2017
liver aplastic, abnormal AB + MO1-klf8 standard conditions Fig. 1 with image from Lin et al., 2017
heart morphology, abnormal AB + MO1-klf8 standard conditions Fig. 1 with image from Lin et al., 2017
pancreas bilateral, abnormal AB + MO1-klf8 standard conditions Fig. 1 with image from Lin et al., 2017
cerebellum development disrupted, abnormal WT + MO1-klf8 standard conditions Fig. 1 with image,  Fig. 6 with image from Tsai et al., 2015
cerebellar Purkinje cell differentiation disrupted, abnormal WT + MO1-klf8 standard conditions Fig. 5 with image from Tsai et al., 2015
eye decreased size, abnormal WT + MO1-klf8 standard conditions Fig. 1 with image from Tsai et al., 2015
cerebellum cell proliferation in hindbrain decreased occurrence, abnormal WT + MO1-klf8 standard conditions Fig. 3 with image from Tsai et al., 2015
cerebellar granule cell decreased amount, abnormal WT + MO1-klf8 standard conditions Fig. 6 with image from Tsai et al., 2015
cerebellum apoptotic process increased occurrence, abnormal WT + MO1-klf8 standard conditions Fig. 3 with image from Tsai et al., 2015
cerebellum morphology, abnormal WT + MO1-klf8 standard conditions Fig. 1 with image from Tsai et al., 2015
Kupffer's vesicle cilium decreased length, abnormal s870Tg + MO1-klf8 standard conditions Fig. 5 with image from Lin et al., 2017
Kupffer's vesicle cilium decreased amount, abnormal s870Tg + MO1-klf8 standard conditions Fig. 5 with image from Lin et al., 2017
whole organism has fewer parts of type forerunner cell group, abnormal s870Tg + MO1-klf8 standard conditions Fig. 5 with image from Lin et al., 2017
Citations
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