ZFIN ID: ZDB-GENE-990630-11
Gene Name: lefty2
Gene Symbol: lft2
Sequence Ontology ID : SO:0000704

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Previous Names: atv2 (1), cb720 (1), fe38b03, wu:fe38b03

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(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have cytokine activity and transforming growth factor beta receptor binding activity; involved in heart field specification and mesoderm development; predicted to localize to the  ...
GENE EXPRESSION
All Expression Data: 94 figures from 74 publications
Directly Submitted Expression Data: 5 figures (33 images) from Thisse et al., 2001 [cb720]
Wild-type Stages, Structures: Blastula:Sphere (4.0h-4.33h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
a146 Small Deletion Unknown Frameshift, Premature Stop TALEN
Targeting reagents:
PHENOTYPE
Data: 6 figures from 4 publications
Observed in:
DISEASE ASSOCIATED WITH lft2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH lft2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process heart field specification (more)
Cellular Component extracellular region (more)
Molecular Function cytokine activity (more)
GO Terms (all 14)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001111 (1)
  • InterPro:IPR001839 (1)
  • InterPro:IPR003942 (1)
  • InterPro:IPR015615 (1)
  • InterPro:IPR017948 (1)
  • InterPro:IPR029034 (1)
  • PROSITE:PS00250 (1)
  • PROSITE:PS51362 (1)
  • Pfam:PF00019 (1)
  • Pfam:PF00688 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lft2-201 (1) 1318
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM lft2 No data available
    MARKER RELATIONSHIPS
    lft2Contained in: [BAC] CH211-236P5 (1) (order this)
    lft2Encodes: [EST] cb720 (1) (order this), fe38b03
    [cDNA] MGC:114024 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_130961 (1) 1315bp
    Genomic GenBank:BX248131 (1) 162685bp
    Select Tool
    Polypeptide UniProtKB:A0A0B5JW28 (1) 362aa
    Sequence Clusters UniGene:80504 (1)
    Sequence Information (all 17)
    OTHER lft2 GENE PAGES
  • Alliance (1)
  • Gene:30146 (1)
  • VEGA:OTTDARG00000020110 (1)
  • Ensembl(GRCz11):ENSDARG00000044059 (1)
  • ORTHOLOGY for lft2 (Chr: 17)
    CITATIONS (142)