Gene
klf8
- ID
- ZDB-GENE-070424-152
- Name
- Kruppel like factor 8
- Symbol
- klf8 Nomenclature History
- Previous Names
-
- si:ch211-208m1.2
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within cerebellar Purkinje cell differentiation; cerebellar granule cell differentiation; and establishment of left/right asymmetry. Is expressed in several structures, including brain; digestive system; optic cup; optic vesicle; and retina. Orthologous to human KLF8 (KLF transcription factor 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Tsai et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|
| UniProtKB:A0A8M2BHN8 | InterPro | 316 | ||
| UniProtKB:A0S0R1 | InterPro | 343 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids