Gene

klf8

ID
ZDB-GENE-070424-152
Name
Kruppel-like factor 8
Symbol
klf8 Nomenclature History
Previous Names
  • si:ch211-208m1.2
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cerebellar Purkinje cell differentiation; cerebellar granule cell differentiation; and establishment of left/right asymmetry. Is expressed in several structures, including brain; digestive system; optic cup; optic vesicle; and retina. Orthologous to human KLF8 (Kruppel like factor 8).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from Tsai et al., 2015
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
9 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With klf8 Human Ortholog
No data available
Associated With klf8 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013087 Zinc finger C2H2-type
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
Domain Details Per Protein
Protein Length Zinc finger C2H2 superfamily Zinc finger C2H2-type
UniProtKB:F1QE84 220
UniProtKB:A0S0R1 343
UniProtKB:A0A2R8QT61 335
UniProtKB:F1QE03 182
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations