Gene

ptf1a

ID
ZDB-GENE-030616-579
Name
pancreas associated transcription factor 1a
Symbol
ptf1a Nomenclature History
Previous Names
  • Ptfa (1)
  • si:zc142h2.2
  • zgc:112216
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Exhibits DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in animal organ development and positive regulation of transcription, DNA-templated. Predicted to localize to cytoplasm; nucleus; and transcription regulator complex. Is expressed in several structures, including central nervous system; exocrine cell; eye; mid intestine; and pancreatic system. Human ortholog(s) of this gene implicated in pancreatic agenesis. Orthologous to human PTF1A (pancreas associated transcription factor 1a).
Genome Resources
Note
None
Expression
All Expression Data
65 figures from 39 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ptf1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Pancreatic agenesis 2 615935
Pancreatic and cerebellar agenesis 609069
Associated With ptf1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Protein Length
UniProtKB:Q7ZSX3 265
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations