ZFIN ID: ZDB-FIG-181115-5
Liu et al., 2017 - Germline-specific dgcr8 knockout in zebrafish using a BACK approach. Cellular and molecular life sciences : CMLS   74(13):2503–2511 Full text @ Cell. Mol. Life Sci.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage Range: Shield to 5-9 somites
PHENOTYPE:
Fish:
Observed In:
Stage Range: Shield to 5-9 somites

Fig. 6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
chrd WT standard conditions Shield presumptive dorsal mesoderm ISH
dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Shield presumptive dorsal mesoderm ISH
gata1a WT standard conditions 5-9 somites erythroid progenitor cell ISH
dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions 5-9 somites erythroid progenitor cell ISH
gsc WT standard conditions Shield presumptive dorsal mesoderm ISH
dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Shield presumptive dorsal mesoderm ISH
nkx2.5 WT standard conditions 5-9 somites heart primordium ISH
dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions 5-9 somites heart primordium ISH
pax2a WT standard conditions 5-9 somites midbrain hindbrain boundary neural rod ISH
5-9 somites otic placode ISH
dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions 5-9 somites midbrain hindbrain boundary neural rod ISH
5-9 somites otic placode ISH
sox17 WT standard conditions 75%-epiboly endoderm ISH
dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions 75%-epiboly endoderm ISH
sox32 WT standard conditions 75%-epiboly endoderm ISH
dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions 75%-epiboly endoderm ISH
spi1b WT standard conditions 5-9 somites myeloid cell ISH
dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions 5-9 somites Not Detected myeloid cell ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Shield presumptive dorsal mesoderm gsc expression decreased distribution, abnormal
Shield presumptive dorsal mesoderm chrd expression decreased distribution, abnormal
75%-epiboly endoderm sox17 expression decreased amount, abnormal
75%-epiboly endoderm sox32 expression decreased amount, abnormal
5-9 somites cardioblast migration to the midline involved in heart field formation decreased occurrence, abnormal
5-9 somites midbrain hindbrain boundary neural rod pax2a expression decreased amount, abnormal
5-9 somites myeloid cell spi1b expression absent, abnormal
5-9 somites otic placode pax2a expression spatial pattern, abnormal
Full text @ Cell. Mol. Life Sci.