ZFIN is now using GRCz12tu for Genomic Data
Gene
sox32
- ID
- ZDB-GENE-011026-1
- Name
- SRY-box transcription factor 32
- Symbol
- sox32 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables DNA binding activity; DNA-binding transcription factor activity; and protein heterodimerization activity. Acts upstream of or within several processes, including circulatory system development; gastrulation; and regulation of endodermal cell fate specification. Predicted to be active in nucleus. Is expressed in several structures, including Kupffer's vesicle; blastoderm; blood island; endoderm; and forerunner cell group. Human ortholog(s) of this gene implicated in 46,XX sex reversal 1; 46,XY sex reversal; and 46,XY sex reversal 1. Orthologous to human SRY (sex determining region Y).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 99 figures from 66 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb527 (18 images)
Wild Type Expression Summary
- All Phenotype Data
- 38 figures from 26 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | High mobility group box domain | High mobility group box domain superfamily | SRY-related HMG-box transcription factor-like |
|---|---|---|---|---|---|
| UniProtKB:Q90Z46 | InterPro | 307 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
- Genome Browsers