FIGURE

Fig. 3

ID

ZDB-FIG-110929-20

Publication

Greenhill et al., 2011 - An iterative genetic and dynamical modelling approach identifies novel features of the gene regulatory network underlying melanocyte development

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Fig. 3

Residual melanocyte marker expression in sox10, mitfa, and sox10;mitfa mutants.

A–AB) Expression of dct, tyr, silva and tyrp1b in wild-type (WT), sox10^t3, mitfa^w2 and sox10^t3; mitfa^w2 mutants is shown at 24 and 36 hpf as indicated. Insets in each panel show enlargement of area of dorsal posterior trunk. Note the pronounced derepression of silva and dct, mild derepression of tyr, and minimal residual expression of tyrp1. Note that all in situs were over-developed in order to detect low level expression.

Expression Data

Genes:	dct pmela tyr tyrp1b
Fish:	WT mitfa^w2/w2 sox10^t3/t3 mitfa^w2/w2; sox10^t3/t3
Anatomical Term:	trunk
Stage Range:	Prim-5 to Prim-25

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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