ZFIN ID: ZDB-GENE-040718-249
Gene Name: tyrosinase-related protein 1b
Gene Symbol: tyrp1b
Previous Names: tyrp1 (1), hm:zeh0659, oca3, zgc:100893
Location: Chr: 1 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 14 figures from 10 publications
Directly Submitted Expression Data: 4 figures (14 images) from Thisse et al., 2004 [IMAGE:6894514]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
  eye, fin, hatching gland, integument (all 13) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents: MO1-tyrp1b (1), MO2-tyrp1b (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH tyrp1b HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
oculocutaneous albinism Albinism, oculocutaneous, type III 203290
[Skin/hair/eye pigmentation, variation in, 11 (Melanesian blond hair)] 612271
GENE ONTOLOGY
Ontology GO Term
Biological Process melanosome organization (more)
Cellular Component integral component of membrane (more)
Molecular Function copper ion binding (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002227 (1)
  • InterPro:IPR008922 (1)
  • InterPro:IPR015559 (1)
  • PROSITE:PS00497 (1)
  • PROSITE:PS00498 (1)
  • Pfam:PF00264 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tyrp1b-001 (1) 1969
    GENE PRODUCT DESCRIPTION No description available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tyrp1b
    Tg(tyrp1b:palm-mCherry)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    tyrp1bContained in: [BAC] CH211-241E15 (1) (order this)
    tyrp1bContains: [SNP] rs3727528 (1), rs3727529 (1)
    tyrp1bEncodes: [EST] fm95g09 (1), IMAGE:6894514 (1) (order this), zeh0659
    [cDNA] MGC:100893 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA GenBank:BC076406 (1) 2000bp
    Genomic GenBank:BX901913 (1) 142370bp
    Select Tool
    Polypeptide UniProtKB:Q6DGE4 (1) 526aa
    Sequence Information (all 7)
    OTHER tyrp1b GENE PAGES
  • VEGA:OTTDARG00000019511 (1)
  • Ensembl(GRCz10):ENSDARG00000056151 (1)
  • ORTHOLOGY for tyrp1b (Chr: 1)
    Species Symbol Chromosome Accession # Evidence
    Human TYRP1 9
  • Gene:7306
  • OMIM:115501
  • HGNC:12450
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (2)
    Mouse Tyrp1 4
  • MGI:98881
  • Gene:22178
  • Amino acid sequence comparison (2)
    Download Curated Orthology
    CITATIONS (32)