ZFIN ID: ZDB-GENE-000508-1
Gene Name: dopachrome tautomerase
Gene Symbol: dct
Previous Names: TRP-2, trp2, tyrosinase-related protein-2, zgc:109860
Location: Chr: 9 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 73 figures from 51 publications
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
  brain, extension, eye, fin (all 26) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
la016638Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21611 Point Mutation ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dct HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process metabolic process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002227 (1)
  • InterPro:IPR008922 (1)
  • PROSITE:PS00497 (1)
  • PROSITE:PS00498 (1)
  • Pfam:PF00264 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA dct-001 (1) 1472
    ncRNA dct-002 (1) 1077
    GENE PRODUCT DESCRIPTION
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM dct No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    dctContained in: [Fosmid] CH1073-495O7 (1) (order this)
    dctEncodes: [cDNA] MGC:109860 (1) (order this), MGC:158512 (1), MGC:191397 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131555 (1) 1884bp
    Genomic GenBank:CU694472 (1) 32900bp
    Select Tool
    Polypeptide UniProtKB:A1L1Y0 (1) 513aa
    Sequence Clusters UniGene:82316 (1)
    Sequence Information (all 27)
    OTHER dct GENE PAGES
  • Gene:58074 (1)
  • VEGA:OTTDARG00000032848 (1)
  • Ensembl(GRCz10):ENSDARG00000006008 (1)
  • ORTHOLOGY for dct (Chr: 9)
    Species Symbol Chromosome Accession # Evidence
    Human DCT 13
  • Gene:1638
  • OMIM:191275
  • HGNC:2709
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (2)
    Mouse Dct 14
  • MGI:102563
  • Gene:13190
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (98)