Gene

dct

ID
ZDB-GENE-000508-1
Name
dopachrome tautomerase
Symbol
dct Nomenclature History
Previous Names
  • TRP-2
  • trp2
  • tyrosinase-related protein-2
  • zgc:109860
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have dopachrome isomerase activity. Predicted to be involved in developmental pigmentation; generation of neurons; and melanin biosynthetic process from tyrosine. Predicted to localize to melanosome. Is expressed in several structures, including eye; female organism; immature eye; integument; and neural crest. Orthologous to human DCT (dopachrome tautomerase).
Genome Resources
Note
None
Expression
All Expression Data
88 figures from 65 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dct Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Oculocutaneous albinism, type VIII 619165
Associated With dct Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002227 Tyrosinase copper-binding domain
Homologous_superfamily IPR008922 Uncharacterised domain, di-copper centre
Domain Details Per Protein
Protein Length Tyrosinase copper-binding domain Uncharacterised domain, di-copper centre
UniProtKB:A1L1Y0 513
UniProtKB:Q9I8G5 513
UniProtKB:F1QRR2 513
UniProtKB:Q4KMK5 404
UniProtKB:F1QMT0 419
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations