ZFIN ID: ZDB-FISH-150901-22193
Fish name: mitfaw2/w2
Genotype: mitfaw2/w2
Targeting Reagent: none
HUMAN DISEASE MODELED by mitfaw2/w2
Human Disease Conditions Citations
cancer cancer xenotransplantation Casey et al., 2017
GENE EXPRESSION
Gene expression in mitfaw2/w2
RNA expression
Expressed Gene Structure Conditions Figures
apoa1a standard conditions Fig. 2 with image,  Fig. 6 with image from Otis et al., 2015
apoa1b standard conditions Fig. 2 with image,  Fig. 6 with image from Otis et al., 2015
apoa4a standard conditions Fig. 5 with image,  Fig. 6 with image from Otis et al., 2015
apoa4b.1 standard conditions Fig. 5 with image,  Fig. 6 with image from Otis et al., 2015
apoa4b.2 standard conditions Fig. 5 with image,  Fig. 6 with image from Otis et al., 2015
apoa4b.3 standard conditions Fig. 5 with image,  Fig. 6 with image from Otis et al., 2015
apoba standard conditions Fig. 3 with image,  Fig. 6 with image from Otis et al., 2015
apobb.1 standard conditions Fig. 3 with image,  Fig. 6 with image from Otis et al., 2015
apobb.2 standard conditions Fig. 3 with image,  Fig. 6 with image from Otis et al., 2015
apoea control Fig. 4 with image,  Fig. 6 with image from Otis et al., 2015
apoeb control Fig. 4 with image,  Fig. 6 with image from Otis et al., 2015
bcl2l11 standard conditions Fig. 6 from Weiner et al., 2019
cxcl12a standard conditions Fig. 1 with image from Isles et al., 2019
amputation: caudal fin Fig. 1 with image from Isles et al., 2019
dct standard conditions Fig. 3 with image from Greenhill et al., 2011
heat shock Fig. 5 with image from Johnson et al., 2011
kitlga standard conditions Fig. 8 with image from Dooley et al., 2013
lrmda standard conditions Fig. 4 from Gronskov et al., 2013
ltk standard conditions Fig 8 with image from Petratou et al., 2021
otx2a standard conditions Fig. 7 with image from Lane et al., 2012
otx2b standard conditions Fig. 7 with image from Lane et al., 2012
pmela standard conditions Fig. 3 with image from Greenhill et al., 2011
slc45a2 standard conditions Fig. 4 from Dooley et al., 2013
sox10 standard conditions Fig. 7 with image,  Fig. S5 with image from Greenhill et al., 2011
chemical treatment: pharmaceutical Fig. S5 with image from Greenhill et al., 2011
tfec standard conditions Fig 8 with image from Petratou et al., 2021
tyr standard conditions Fig. 3 with image from Greenhill et al., 2011
tyrp1b standard conditions Fig. 3 with image from Greenhill et al., 2011
urp1 standard conditions Fig. 1 with image from Quan et al., 2015
zgc:100846 standard conditions Fig. 3 from Ciura et al., 2013
Protein expression No data available
Reporter gene expression No data available
PHENOTYPE
Phenotype in mitfaw2/w2
Phenotype Conditions Figures
caudal fin cxcl12a expression increased amount, abnormal amputation: caudal fin Fig. 1 with image from Isles et al., 2019
dorsal larval melanophore stripe melanocyte normal amount, normal standard conditions Fig 4 with image from Petratou et al., 2021
eye has normal numbers of parts of type iridophore, normal standard conditions Fig. 1 with image from Antinucci et al., 2016
eye pigmented, normal standard conditions Fig. 1 with image from Antinucci et al., 2016
head dorsal region increased accumulation melanocyte, abnormal standard conditions Fig 4 with image from Petratou et al., 2021
larval melanophore stripe melanocyte absent, abnormal standard conditions Fig. 1 with image from Antinucci et al., 2016
lateral larval melanophore stripe melanocyte normal amount, normal standard conditions Fig 4 with image from Petratou et al., 2021
melanocyte absent, abnormal standard conditions Fig. 6 with image from Fadeev et al., 2015
Fig. 5 with image from Irion et al., 2014
Fig. S1 from Mahalwar et al., 2014
Fig. 2 with image from Johnson et al., 2011
melanocyte absent, abnormal heat shock Fig. 1 with image from Johnson et al., 2011
melanocyte decreased amount, abnormal heat shock Fig. 1 with image from Johnson et al., 2011
melanophore stripe absent, abnormal standard conditions Fig. 4 with image from Eskova et al., 2017
melanophore stripe morphology, abnormal standard conditions Fig. 4 with image from Eskova et al., 2017
melanophore stripe melanocyte absent, abnormal standard conditions Fig. 1 with image from Antinucci et al., 2016
optic fissure closed, normal standard conditions Fig. 1 with image from Sinagoga et al., 2020
optic fissure basement membrane absent, normal standard conditions Fig. 1 with image from Sinagoga et al., 2020
pigmentation disrupted, abnormal standard conditions Fig. 5 with image from Irion et al., 2014
retinal pigmented epithelium decreased pigmentation, abnormal standard conditions Fig. 1 with image from Antinucci et al., 2016
retinal pigmented epithelium pigmented, normal standard conditions Fig. 1 with image from Antinucci et al., 2016
swimming behavior process quality, abnormal standard conditions Fig. 4 from Stowers et al., 2017
trunk dermis lacks all parts of type melanocyte, abnormal standard conditions Fig. 8 with image from Frohnhöfer et al., 2013
trunk dorsal region tfec expression increased amount, abnormal standard conditions Fig 8 with image from Petratou et al., 2021
trunk iridophore mislocalised, abnormal standard conditions Fig. 3 with image,  Fig. 8 with image from Frohnhöfer et al., 2013
ventral larval melanophore stripe melanocyte normal amount, normal standard conditions Fig 4 with image from Petratou et al., 2021
whole organism bcl2l11 expression decreased amount, abnormal standard conditions Fig. 6 from Weiner et al., 2019
whole organism lacks all parts of type melanocyte, abnormal standard conditions Fig. 3 with image from Frohnhöfer et al., 2013
whole organism melanocyte absent, abnormal standard conditions Fig 4 with image from Petratou et al., 2021
whole organism melanoma neoplastic, metastatic, abnormal cancer xenotransplantation Fig. 9 with image from Deiana et al., 2018
whole organism melanoma present, abnormal cancer xenotransplantation Fig. 9 with image from Deiana et al., 2018

CITATIONS  (82)

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