ZFIN Figure: Greenhill et al., 2011, Fig. S5

ZFIN ID: ZDB-FIG-110929-31

ZFIN ID: ZDB-FIG-110929-31

Greenhill et al., 2011 - An iterative genetic and dynamical modelling approach identifies novel features of the gene regulatory network underlying melanocyte development. PLoS Genetics 7(9):e1002265 Full text @ PLoS Genet.

ADDITIONAL FIGURES

EXPRESSION / LABELING:

Gene:	sox10
Fish:	mitfa^w2/w2
Condition:	chemical treatment: pharmaceutical
Anatomical Terms:	head cell neural crest trunk cell
Stage Range:	Prim-5 to Prim-25

Fig. S5

Hdac-dependent derepression of sox10 expression is not seen in mitfa mutant embryos. A–F) In situ hybridisation with sox10 probe showing similar levels of sox10 expression in premigratory (arrow, C) and migrating (arrowhead, C) neural crest cells of mitfa mutants whether treated with 1 μM Trichostatin A from 24–48 hpf (B,D,F) or in stage-matched 36 hpf DMSO control mitfa mutants (A,C,E). Compare effect in WT embryos shown in Figure 8. Scale bar: 100 μm.

Gene Expression Details

Gene	Fish	Conditions	Stage	Anatomy	Assay
sox10	mitfa^w2/w2	control	Prim-25	head cell	ISH
			Prim-25	trunk cell	ISH
	mitfa^w2/w2	chemical treatment: pharmaceutical	Prim-5	neural crest	ISH

Antibody Labeling Details No data available

Phenotype Details No data available

Acknowledgments:
ZFIN wishes to thank the journal PLoS Genetics for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS Genet.