Fig. 2

Xu et al., 2010 - Setdb2 restricts dorsal organizer territory and regulates left-right asymmetry through suppressing fgf8 activity
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Fig. 2

Organ laterality is randomized in setdb2-knockdown embryos. (A–L) Whole-mount mRNA in situ hybridization and statistical analyses of visceral and diencephalic laterality in the 5-MM control and setdb2 MO2-injected embryos at the indicated developmental stages with probes cmlc2 (A–C), lefty1 (DF), cebpα (GI, arrows), and insulin (JL). (MO) Determination of pancreatic laterality in 72-hpf Tg(insulin:EGFP) transgenic embryos injected with 5-MM control and setdb2 MO2. Dashed lines denote the embryonic midline. LV, liver; G, gut; L, Left side; R, Right side; C/B, central or bilateral; A, absent. All embryos are dorsal views with head to the top.

Expression Data
Knockdown Reagent:
Anatomical Terms:
Stage Range: 20-25 somites to Protruding-mouth

Expression Detail
Antibody Labeling
Phenotype Data
Knockdown Reagent:
Observed In:
Stage Range: 20-25 somites to Protruding-mouth

Phenotype Detail
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