Gene

cebpa

ID
ZDB-GENE-020111-2
Name
CCAAT enhancer binding protein alpha
Symbol
cebpa Nomenclature History
Previous Names
  • c/ebpa (1)
  • cb1062 (1)
  • chunp6777
  • fj20f03
  • unm_sm1120
  • wu:fj20f03 (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Exhibits DNA binding activity and DNA-binding transcription factor activity. Involved in hematopoietic stem cell migration; hemopoiesis; and liver development. Predicted to localize to nucleus. Is expressed in several structures, including digestive system; hematopoietic cell; hematopoietic system; mesoderm; and yolk syncytial layer. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human CEBPA (CCAAT enhancer binding protein alpha).
Genome Resources
Note
None
Expression
All Expression Data
43 figures from 34 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cebpa Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
acute myeloid leukemia Alliance Leukemia, acute myeloid, somatic 601626
acute myeloid leukemia Alliance ?Leukemia, acute myeloid 601626
Associated With cebpa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004827 Basic-leucine zipper domain
Family IPR016468 CCAAT/enhancer-binding protein, chordates
Domain Details Per Protein
Protein Length Basic-leucine zipper domain CCAAT/enhancer-binding protein, chordates
UniProtKB:Q8UVZ1 288
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations