Ajouaou, Y., Magnani, E., Madakashira, B., Jenkins, E., Sadler, K.C. (2023) atm Mutation and Oxidative Stress Enhance the Pre-Cancerous Effects of UHRF1 Overexpression in Zebrafish Livers. Cancers. 15(8):

Bian, L., Nguyen, V.T., Tamaoki, J., Endo, Y., Dong, G., Sato, A., Kobayashi, M. (2023) Genetic hyperactivation of Nrf2 causes larval lethality in Keap1a and Keap1b-double-knockout zebrafish. Redox Biology. 62:102673

Chen, M., Luo, Y., Xu, J., Chang, M.X., Liu, J.X. (2019) Copper Regulates the Susceptibility of Zebrafish Larvae to Inflammatory Stimuli by Controlling Neutrophil/Macrophage Survival. Frontiers in immunology. 10:2599

Delaney, P., Ramdas Nair, A., Palmer, C., Khan, N., Sadler, K.C. (2020) Arsenic induced redox imbalance triggers the unfolded protein response in the liver of zebrafish. Toxicology and applied pharmacology. 409:115307

Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549

Garcia-Reyero, N., Escalon, L., Prats, E., Faria, M., Soares, A.M., Raldúa, D. (2016) Targeted Gene Expression in Zebrafish Exposed to Chlorpyrifos-Oxon Confirms Phenotype-Specific Mechanisms Leading to Adverse Outcomes. Bulletin of environmental contamination and toxicology. 96(6):707-713

Harris, J.M., Esain, V., Frechette, G.M., Harris, L.J., Cox, A.G., Cortes, M., Garnaas, M.K., Carroll, K.J., Cutting, C.C., Khan, T., Elks, P.M., Renshaw, S.A., Dickinson, B.C., Chang, C.J., Murphy, M.P., Paw, B.H., Vander Heiden, M.G., Goessling, W., and North, T.E. (2013) Glucose metabolism impacts the spatio-temporal onset and magnitude of HSC induction in vivo. Blood. 121(13):2483-2493

Henry, T.B., Menn, F.M., Fleming, J.T., Wilgus, J., Compton, R.N., and Sayler, G.S. (2007) Attributing effects of aqueous C60 nano-aggregates to tetrahydrofuran decomposition products in larval zebrafish by assessment of gene expression. Environmental health perspectives. 115(7):1059-1065

Jeon, H.J., Lee, Y.H., Kim, M.J., Choi, S.D., Park, B.J., Lee, S.E. (2016) Integrated biomarkers induced by chlorpyrifos in two different life stages of zebrafish (Danio rerio) for environmental risk assessment. Environmental Toxicology and Pharmacology. 43:166-174

Kim, C., Choe, H., Park, J., Kim, G., Kim, K., Jeon, H.J., Moon, J.K., Kim, M.J., Lee, S.E. (2020) Molecular mechanisms of developmental toxicities of azoxystrobin and pyraclostrobin toward zebrafish (Danio rerio) embryos: Visualization of abnormal development using two transgenic lines. Environmental pollution (Barking, Essex : 1987). 270:116087

Kim, Y.C., Lee, S.R., Jeon, H.J., Kim, K., Kim, M.J., Choi, S.D., Lee, S.E. (2020) Acute toxicities of fluorene, fluorene-1-carboxylic acid, and fluorene-9-carboxylic acid on zebrafish embryos (Danio rerio): Molecular mechanisms of developmental toxicities of fluorene-1-carboxylic acid. Chemosphere. 260:127622

Kwok, M.L., Hu, X.L., Meng, Q., Chan, K.M. (2020) Whole-transcriptome sequencing (RNA-seq) analyses of the zebrafish liver cell line, ZFL, after acute exposure to Cu²⁺ ions. Metallomics : integrated biometal science. 12(5):732-751

Leask, M., Carleton, C., Leeke, B., Newman, T., Antoun, J., Farella, M., Horsfield, J. (2021) Riboceine Rescues Auranofin-Induced Craniofacial Defects in Zebrafish. Antioxidants (Basel, Switzerland). 10(12):

Liu, G.P., Xiang, L.X., Shao, T., Lin, A.F., Shao, J.Z. (2018) Stimulatory function of peroxiredoxin 1 in activating adaptive humoral immunity in a zebrafish model. Developmental and comparative immunology. 84:353-360

Lu, X., Xiang, Y., Yang, G., Zhang, L., Wang, H., Zhong, S. (2017) Transcriptomic characterization of zebrafish larvae in response to mercury exposure. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 192:40-49

Ma, J., Shao, X., Geng, F., Liang, S., Yu, C., Zhang, R. (2022) Ercc2/Xpd deficiency results in failure of digestive organ growth in zebrafish with elevated nucleolar stress. iScience. 25:104957

Mills, M.G., Gallagher, E.P. (2017) A targeted gene expression platform allows for rapid analysis of chemical-induced antioxidant mRNA expression in zebrafish larvae. PLoS One. 12:e0171025

Mukaigasa, K., Nguyen, L.T., Li, L., Nakajima, H., Yamamoto, M., and Kobayashi, M. (2012) Genetic Evidence of an Evolutionarily Conserved Role for Nrf2 in the Protection against Oxidative Stress. Molecular and cellular biology. 32(21):4455-4461

Newman, T.A., Carleton, C.R., Leeke, B., Hampton, M.B., Horsfield, J.A. (2015) Embryonic oxidative stress results in reproductive impairment for adult zebrafish. Redox Biology. 6:648-655

Nguyen, V.T., Bui Thị Thu, V., Vo Thi Minh, T., Huynh Vinh, K., Lam Vy, N., Nguyen Hoang Thuy, V., Luu Pham, T., Xuan Nguyen, T., Thi Thuy, D., Huynh, H.D., Nguyen, T.G. (2025) UPLC-QTOF-MS/MS-Guided phytochemical characterization and molecular docking of Rosa rusoga extract for Keap1-Nrf2 modulation. Natural Product Research. :191-9

Parida, S., Mohapatra, A., Sahoo, P.K. (2020) Cloning and functional characterisation of natural killer enhancing factor-B (NKEF-B) gene of Labeo rohita: Anti-oxidant and antimicrobial activities of its recombinant protein. Molecular immunology. 126:73-86

Park, K.H., Kim, S.H. (2019) Low dose of chronic ethanol exposure in adult zebrafish induces hepatic steatosis and injury. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 117:109179

Peng, Y., Li, M., Huang, Y., Cheng, B., Cao, Z., Liao, X., Xiong, G., Liu, F., Hu, C., Lu, H. (2021) Bifenazate induces developmental and immunotoxicity in zebrafish. Chemosphere. 271:129457

Raghunath, A., Nagarajan, R., Sundarraj, K., Panneerselvam, L., Perumal, E. (2018) Genome-wide identification and analysis of Nrf2 binding sites - Antioxidant response elements in zebrafish. Toxicology and applied pharmacology. 360:236-248

Rainieri, S., Conlledo, N., Larsen, B.K., Granby, K., Barranco, A. (2018) Combined effects of microplastics and chemical contaminants on the organ toxicity of zebrafish (Danio rerio). Environmental research. 162:135-143

Song, Y.C., Wu, B.J., Chiu, C.C., Chen, C.L., Zhou, J.Q., Liang, S.R., Duh, C.Y., Sung, P.J., Wen, Z.H., Wu, C.Y. (2017) Coral-Derived Natural Marine Compound GB9 Impairs Vascular Development in Zebrafish. International Journal of Molecular Sciences. 18(8)

Ton, C., Hwang, D.M., Dempsey, A.A., Tang, H.C., Yoon, J., Lim, M., Mably, J.D., Fishman, M.C., and Liew, C.C. (2000) Identification, characterization, and mapping of expressed sequence tags from an embryonic zebrafish heart cDNA library. Genome research. 10(12):1915-1927

Unal Eroglu, A., Mulligan, T.S., Zhang, L., White, D.T., Sengupta, S., Nie, C., Lu, N.Y., Qian, J., Xu, L., Pei, W., Burgess, S.M., Saxena, M.T., Mumm, J.S. (2018) Multiplexed CRISPR/Cas9 Targeting of Genes Implicated in Retinal Regeneration and Degeneration. Frontiers in cell and developmental biology. 6:88

Wang, L., and Gallagher, E.P. (2013) Role of Nrf2 antioxidant defense in mitigating cadmium-induced oxidative stress in the olfactory system of zebrafish. Toxicology and applied pharmacology. 266(2):177-186

Webb, K.J., Norton, W.H.J., Trumbach, D., Meijer, A.H., Ninkovic, J., Topp, S., Heck, D., Marr, C., Wurst, W., Theis, F.J., Spaink, H.P., and Bally-Cuif, L. (2009) Zebrafish reward mutants reveal novel transcripts mediating the behavioral effects of amphetamine. Genome biology. 10(7):R81

Xu, H., Jiang, Y., Li, S., Xie, L., Tao, Y.X., Li, Y. (2020) Zebrafish Oxr1a Knockout Reveals Its Role in Regulating Antioxidant Defenses and Aging. Genes. 11(10):

Yamashita, A., Deguchi, J., Honda, Y., Yamada, T., Miyawaki, I., Nishimura, Y., Tanaka, T. (2019) Increased susceptibility to oxidative stress-induced toxicological evaluation by genetically modified nrf2a-deficient zebrafish. Journal of Pharmacological and Toxicological Methods. 96:34-45

Yang, L., Kemadjou, J.R., Zinsmeister, C., Legradi, J., Bauer, M., Muller, F., Pankratz, M., Jakel, J., and Straehle, U. (2007) Transcriptional profiling reveals barcode-like toxicogenomic responses in the zebrafish embryo. Genome biology. 8(10):R227

Zhang, X., Zhou, Q., Li, X., Zou, W., Hu, X. (2020) Integrating omics and traditional analyses to profile the synergistic toxicity of graphene oxide and triphenyl phosphate. Environmental pollution (Barking, Essex : 1987). 263:114473

Nguyen, V.T., Bui Thị Thu, V., Vo Thi Minh, T., Huynh Vinh, K., Lam Vy, N., Nguyen Hoang Thuy, V., Luu Pham, T., Xuan Nguyen, T., Thi Thuy, D., Huynh, H.D., Nguyen, T.G. (2025) UPLC-QTOF-MS/MS-Guided phytochemical characterization and molecular docking of Rosa rusoga extract for Keap1-Nrf2 modulation. Natural Product Research. :191-9

Lu, X., Zhang, L., Lin, G.M., Lu, J.G., Cui, Z.B. (2024) Analysis of Differential Gene Expression under Acute Lead or Mercury Exposure in Larval Zebrafish Using RNA-Seq. Animals : an open access journal from MDPI. 14(19):

Ajouaou, Y., Magnani, E., Madakashira, B., Jenkins, E., Sadler, K.C. (2023) atm Mutation and Oxidative Stress Enhance the Pre-Cancerous Effects of UHRF1 Overexpression in Zebrafish Livers. Cancers. 15(8):

Park, J., MacGavin, S., Niederbrach, L., Mchaourab, H.S. (2023) Interplay between Nrf2 and αB-crystallin in the lens and heart of zebrafish under proteostatic stress. Frontiers in molecular biosciences. 10:1185704

Katayama, Y., Saito, A., Ogoshi, M., Tsuneoka, Y., Mukuda, T., Azuma, M., Kusakabe, M., Takei, Y., Tsukada, T. (2022) Gene duplication of C-type natriuretic peptide-4 (CNP4) in teleost lineage elicits subfunctionalization of ancestral CNP. Cell and tissue research. 388(2):225-238

Watanabe, A., Muraki, K., Tamaoki, J., Kobayashi, M. (2022) Soy-Derived Equol Induces Antioxidant Activity in Zebrafish in an Nrf2-Independent Manner. International Journal of Molecular Sciences. 23(9)

Leask, M., Carleton, C., Leeke, B., Newman, T., Antoun, J., Farella, M., Horsfield, J. (2021) Riboceine Rescues Auranofin-Induced Craniofacial Defects in Zebrafish. Antioxidants (Basel, Switzerland). 10(12):

Peng, Y., Li, M., Huang, Y., Cheng, B., Cao, Z., Liao, X., Xiong, G., Liu, F., Hu, C., Lu, H. (2021) Bifenazate induces developmental and immunotoxicity in zebrafish. Chemosphere. 271:129457

Kim, C., Choe, H., Park, J., Kim, G., Kim, K., Jeon, H.J., Moon, J.K., Kim, M.J., Lee, S.E. (2020) Molecular mechanisms of developmental toxicities of azoxystrobin and pyraclostrobin toward zebrafish (Danio rerio) embryos: Visualization of abnormal development using two transgenic lines. Environmental pollution (Barking, Essex : 1987). 270:116087

Kwok, M.L., Hu, X.L., Meng, Q., Chan, K.M. (2020) Whole-transcriptome sequencing (RNA-seq) analyses of the zebrafish liver cell line, ZFL, after acute exposure to Cu²⁺ ions. Metallomics : integrated biometal science. 12(5):732-751

Nguyen, V.T., Bian, L., Tamaoki, J., Otsubo, S., Muratani, M., Kawahara, A., Kobayashi, M. (2020) Generation and characterization of keap1a- and keap1b-knockout zebrafish. Redox Biology. 36:101667

Volz, S.N., Hausen, J., Nachev, M., Ottermanns, R., Schiwy, S., Hollert, H. (2020) Short exposure to cadmium disrupts the olfactory system of zebrafish (Danio rerio) - Relating altered gene expression in the olfactory organ to behavioral deficits. Aquatic toxicology (Amsterdam, Netherlands). 226:105555

Zhang, X., Zhou, Q., Li, X., Zou, W., Hu, X. (2020) Integrating omics and traditional analyses to profile the synergistic toxicity of graphene oxide and triphenyl phosphate. Environmental pollution (Barking, Essex : 1987). 263:114473

Chen, M., Luo, Y., Xu, J., Chang, M.X., Liu, J.X. (2019) Copper Regulates the Susceptibility of Zebrafish Larvae to Inflammatory Stimuli by Controlling Neutrophil/Macrophage Survival. Frontiers in immunology. 10:2599

Park, K.H., Kim, S.H. (2019) Low dose of chronic ethanol exposure in adult zebrafish induces hepatic steatosis and injury. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 117:109179

Raghunath, A., Nagarajan, R., Sundarraj, K., Palanisamy, K., Perumal, E. (2019) Identification of compounds that inhibit the binding of Keap1a/Keap1b Kelch DGR domain with Nrf2 ETGE/DLG motifs in zebrafish. Basic & Clinical Pharmacology & Toxicology. 125(3):259-270

Yamashita, A., Deguchi, J., Honda, Y., Yamada, T., Miyawaki, I., Nishimura, Y., Tanaka, T. (2019) Increased susceptibility to oxidative stress-induced toxicological evaluation by genetically modified nrf2a-deficient zebrafish. Journal of Pharmacological and Toxicological Methods. 96:34-45

Komoike, Y., Matsuoka, M. (2018) In vitro and in vivo studies of oxidative stress responses against acrylamide toxicity in zebrafish. Journal of hazardous materials. 365:430-439

Raghunath, A., Nagarajan, R., Sundarraj, K., Panneerselvam, L., Perumal, E. (2018) Genome-wide identification and analysis of Nrf2 binding sites - Antioxidant response elements in zebrafish. Toxicology and applied pharmacology. 360:236-248

Unal Eroglu, A., Mulligan, T.S., Zhang, L., White, D.T., Sengupta, S., Nie, C., Lu, N.Y., Qian, J., Xu, L., Pei, W., Burgess, S.M., Saxena, M.T., Mumm, J.S. (2018) Multiplexed CRISPR/Cas9 Targeting of Genes Implicated in Retinal Regeneration and Degeneration. Frontiers in cell and developmental biology. 6:88

Kim, K., Jeon, H.J., Choi, S.D., Tsang, D.C.W., Oleszczuk, P., Ok, Y.S., Lee, H.S., Lee, S.E. (2017) Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio). Chemosphere. 194:30-41

Mills, M.G., Gallagher, E.P. (2017) A targeted gene expression platform allows for rapid analysis of chemical-induced antioxidant mRNA expression in zebrafish larvae. PLoS One. 12:e0171025

Song, Y.C., Wu, B.J., Chiu, C.C., Chen, C.L., Zhou, J.Q., Liang, S.R., Duh, C.Y., Sung, P.J., Wen, Z.H., Wu, C.Y. (2017) Coral-Derived Natural Marine Compound GB9 Impairs Vascular Development in Zebrafish. International Journal of Molecular Sciences. 18(8)

Jeon, H.J., Lee, Y.H., Kim, M.J., Choi, S.D., Park, B.J., Lee, S.E. (2016) Integrated biomarkers induced by chlorpyrifos in two different life stages of zebrafish (Danio rerio) for environmental risk assessment. Environmental Toxicology and Pharmacology. 43:166-174

Fuse, Y., Nakajima, H., Nakajima-Takagi, Y., Nakajima, O., Kobayashi, M. (2015) Heme-mediated inhibition of Bach1 regulates the liver specificity and transience of the Nrf2-dependent induction of zebrafish heme oxygenase 1. Genes to cells : devoted to molecular & cellular mechanisms. 20(7):590-600

Cox, A.G., Saunders, D.C., Kelsey, P.B., Conway, A.A., Tesmenitsky, Y., Marchini, J.F., Brown, K.K., Stamler, J.S., Colagiovanni, D.B., Rosenthal, G.J., Croce, K.J., North, T.E., and Goessling, W. (2014) S-Nitrosothiol Signaling Regulates Liver Development and Improves Outcome following Toxic Liver Injury. Cell Reports. 6(1):56-69

Ho, N.Y., Yang, L., Legradi, J., Armant, O., Takamiya, M., Rastegar, S., and Strähle, U. (2013) Gene Responses in the Central Nervous System of Zebrafish Embryos Exposed to the Neurotoxicant Methyl Mercury. Environmental science & technology. 47(7):3316-25

Tsedensodnom, O., Vacaru, A.M., Howarth, D.L., Yin, C., and Sadler, K.C. (2013) Ethanol metabolism and oxidative stress are required for unfolded protein response activation and steatosis in zebrafish with alcoholic liver disease. Disease models & mechanisms. 6(5):1213-26

Mukaigasa, K., Nguyen, L.T., Li, L., Nakajima, H., Yamamoto, M., and Kobayashi, M. (2012) Genetic Evidence of an Evolutionarily Conserved Role for Nrf2 in the Protection against Oxidative Stress. Molecular and cellular biology. 32(21):4455-4461

Yang, L., Ho, N.Y., Muller, F., and Strahle, U. (2010) Methyl mercury suppresses the formation of the tail primordium in developing zebrafish embryos. Toxicological sciences : an official journal of the Society of Toxicology. 115(2):379-390

Henry, T.B., Menn, F.M., Fleming, J.T., Wilgus, J., Compton, R.N., and Sayler, G.S. (2007) Attributing effects of aqueous C60 nano-aggregates to tetrahydrofuran decomposition products in larval zebrafish by assessment of gene expression. Environmental health perspectives. 115(7):1059-1065

Link, V., Shevchenko, A., and Heisenberg, C.P. (2006) Proteomics of early zebrafish embryos. BMC Developmental Biology. 6:1

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

Geisler, R., Rauch, G.J., Baier, H., van Bebber, F., Brobeta, L., Dekens, M.P., Finger, K., Fricke, C., Gates, M.A., Geiger, H., Geiger-Rudolph, S., Gilmour, D., Glaser, S., Gnugge, L., Habeck, H., Hingst, K., Holley, S., Keenan, J., Kirn, A., Knaut, H., Lashkari, D., Maderspacher, F., Martyn, U., Neuhauss, S., Neumann, C., Nicolson, T., Pelegri, F., Ray, R., Rick, J.M., Roehl, H., Roeser, T., Schauerte, H.E., Schier, A.F., Schönberger, U., Schönthaler, H.-B., Schulte-Merker, S., Seydler, C., Talbot, W.S., Weiler, C., Nüsslein-Volhard, C., and Haffter, P. (1999) A radiation hybrid map of the zebrafish genome. Nature Genetics. 23(1):86-89