FIGURE

Fig. 8

ID

ZDB-FIG-260618-2

Publication

Martin et al., 2026 - Nr2f1a and Isl1 repress acquisition of epicardial identity in venous atrial cardiomyocytes

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Fig. 8

nr2f1a;isl1 mutant atrial cardiomyocytes have ectopic ventricular and epicardial marker expression. (A,B) UMAPs displaying the cell clusters identified and the conditions of the cells from the single-cell transcriptomics of the 96 hpf wild-type, isl1 mutant, nr2f1a mutant and nr2f1a;isl1 mutant hearts. (C) UMAPs showing the subclusters (top) and the conditions (bottom) of the cells from the atrial cardiomyocytes (ACs). (D-F) UMAPs (left) and violin plots (right) of the AC subclusters displaying expression of mybpc3, myh7l and tbx18.

Expression Data

Genes:	mybpc3 myh7l tbx18
Fish:	isl1a^{ci1032/ci1032}; sd7Tg/sd7Tg nr2f1a^{ci1009/ci1009}; sd7Tg/sd7Tg isl1a^{ci1032/ci1032}; nr2f1a^{ci1009/ci1009}; sd7Tg/sd7Tg
Stage:	Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	isl1a^{ci1032/ci1032}; sd7Tg/sd7Tg nr2f1a^{ci1009/ci1009}; sd7Tg/sd7Tg isl1a^{ci1032/ci1032}; nr2f1a^{ci1009/ci1009}; sd7Tg/sd7Tg
Stage:	Day 4

Phenotype Detail

Acknowledgments

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