FIGURE

Fig. 4

ID
ZDB-FIG-210205-28
Publication
Ye et al., 2020 - hox13 genes are required for mesoderm formation and axis elongation during early zebrafish development
Other Figures
All Figure Page
Back to All Figure Page
Fig. 4

Mesodermal defects in hoxa13;ntlcs embryos maintained at 18.5°C. In situ hybridization of 15-somite wild-type and hoxa13;ntlcs embryos. (A). In mutant embryos, expression of tbxta at the posterior end (NMp domain) of the embryo is absent, whereas expression in the notochord progenitors (gray arrowhead) is retained. Note that in mutant embryos tbxta expression in the notochord is normal (black arrowheads). (B-D) Expression of wnt3a (B), wnt8a (C) and cyp26a1 (D) are strongly downregulated in the posterior of mutant embryos. (E,F) Expression of cdx4 (E) and fgf8a (F) are largely normal or only partially reduced in the posterior of mutant embryos. (G) sox2 expression expands into the mesodermal progenitor region in the mutants, whereas in wild-type embryos sox2 is absent from this region (black arrowheads). (H-J) tbx16 (H), msgn1 (I) and pcdh8 (J) are strongly downregulated in mutant embryos. A-G show side views and H-J show dorsal views.

Expression Data
Genes:
Fish:
Anatomical Terms:
Stage: 14-19 somites

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage: 14-19 somites

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development