Gene
tbxta
- ID
- ZDB-GENE-980526-437
- Name
- T-box transcription factor Ta
- Symbol
- tbxta Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Exhibits sequence-specific DNA binding activity and transcription regulatory region DNA binding activity. Involved in several processes, including Kupffer's vesicle development; animal organ development; and regulation of embryonic development. Localizes to nuclear chromatin. Human ortholog(s) of this gene implicated in neural tube defect. Is expressed in several structures, including blastoderm; germ ring; mesoderm; presumptive structure; and tail bud. Orthologous to human TBXT (T-box transcription factor T).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 552 figures from 386 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb240 (18 images)
Wild Type Expression Summary
- All Phenotype Data
- 52 figures from 35 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018186 | Transcription factor, T-box, conserved site |
| Domain | IPR046360 | T-box transcription factor, DNA-binding domain |
| Family | IPR001699 | T-box transcription factor |
| Family | IPR002070 | Transcription factor, Brachyury |
| Homologous_superfamily | IPR008967 | p53-like transcription factor, DNA-binding domain superfamily |
| Homologous_superfamily | IPR036960 | T-box superfamily |
Domain Details Per Protein
| Protein | Length | p53-like transcription factor, DNA-binding domain superfamily | T-box superfamily | T-box transcription factor | T-box transcription factor, DNA-binding domain | Transcription factor, Brachyury | Transcription factor, T-box, conserved site |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q07998
|
423 |
Interactions and Pathways
No data available
Plasmids
No data available