header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030909-1
Gene Name: SRY-box transcription factor 2
Gene Symbol: sox2
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: soxp (1), cb236 (1), wu:fb83g04, wu:fc14d07, zgc:65860, zgc:77389

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 22 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits chromatin binding activity and sequence-specific DNA binding activity; contributes to DNA-binding activity transcription factor activity; involved in several processes, including animal  ...
GENE EXPRESSION
All Expression Data: 129 figures from 75 publications
Directly Submitted Expression Data: 12 figures (28 images) from Rauch et al., 2003 [fb83g04]
  6 figures (19 images) from Thisse et al., 2001 [cb236]
Wild-type Stages, Structures: Blastula:Sphere (4.0h-4.33h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
x50 Small Deletion Unknown Frameshift, Premature Stop TALEN
Targeting reagents:
DISEASE ASSOCIATED WITH sox2 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
microphthalmia Microphthalmia, syndromic 3 206900
Optic nerve hypoplasia and abnormalities of the central nervous system 206900
DISEASE ASSOCIATED WITH sox2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process positive regulation of DNA-binding transcription factor activity (more)
Cellular Component transcription factor complex (more)
Molecular Function chromatin binding (more)
GO Terms (all 24)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA sox2-201 (1) 2072
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIES
PLASMIDSNo data available
CONSTRUCTS WITH SEQUENCES FROM sox2
MARKER RELATIONSHIPS
sox2Contained in: [BAC] CH73-242D14 (1) (order this)
sox2Encodes: [EST] cb236 (1), fb83g04 (1) (order this), fc14d07 (1)
[cDNA] MGC:65860 (1) (order this), MGC:77389 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_213118 (1) 2120bp
Genomic GenBank:FP102167 (1) 98106bp
Select Tool
Polypeptide UniProtKB:Q6P0E1 (1) 315aa
Sequence Clusters UniGene:5379 (1)
Sequence Information (all 20)
ORTHOLOGY for sox2 (Chr: 22)
CITATIONS (184)