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ZIRC
ZFIN ID: ZDB-GENE-030722-1
Gene Name: mesogenin 1
Gene Symbol: msgn1    Nomenclature History

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Previous Names: mespo (1), pMeso1a (1), wu:fc39h09, zgc:109769

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in paraxial mesodermal cell differentiation; regulation of transcription by RNA polymerase II; and somatic muscle development. Predicted to localize to the nucleus. Is expressed in fin; margin; mesoderm; myoblast; and tail bud. Orthologous to human MSGN1 (mesogenin 1).
Genome Resources: Alliance (1),  Gene:360135 (1),  Ensembl(GRCz11):ENSDARG00000070546 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh273 Point Mutation Unknown Premature Stop ENU
  • China Zebrafish Resource Center (CZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • msgn1_unrecovered Point Mutation Unknown Unknown ENU
    sa33349 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-msgn1 N/A 5
    DISEASE ASSOCIATED WITH msgn1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH msgn1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process mesoderm development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 13)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA msgn1-201 (1)    Ensembl 1971
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM msgn1
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(hsp70l:HA-msgn1,Xla.Cryg:ECFP) hsp70l ECFPmsgn1 Danio rerioXenopus laevis 1 2
    Tg(hsp70l:msgn1-2A-NLS-KikGR) hsp70l 2AKikGRmsgn1NLS Danio rerio 1 2
    Tg(msgn1:Cre-ERT2) msgn1 CreERT2 Danio rerio 1 5
    Tg(msgn1:NLS-Kaede) msgn1 KaedeNLS Danio rerio 1 3
    MARKER RELATIONSHIPS
    msgn1 Contained in: [BAC] CH211-222H17 (1) (order this), CH211-249I14 (1) (order this)
    msgn1 Encodes: [EST] fc39h09, wz13339
    [cDNA] MGC:109769 (1) (order this), MGC:174017 (1) (order this), MGC:192585 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_182882 (1) 1674 bp
    Genomic GenBank:BX890562 (1) 195554 bp
    Select Tool
    Polypeptide UniProtKB:B2RY95 (1) 131 aa
    Sequence Clusters UniGene:106405 (1)
    Sequence Information (all 33)
    ORTHOLOGY for msgn1 ( Chr: 4 )
    CITATIONS (54)