Gene

cyp26a1

ID
ZDB-GENE-990415-44
Name
cytochrome P450, family 26, subfamily A, polypeptide 1
Symbol
cyp26a1 Nomenclature History
Previous Names
  • cb24 (1)
  • etID42255.12 (1)
  • gir
  • giraffe
  • id:ibd5061 (1)
  • P450RAI
  • wu:fb81e05 (1)
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Exhibits retinoic acid 4-hydroxylase activity. Involved in several processes, including animal organ development; cellular response to vitamin A; and retinoid metabolic process. Predicted to localize to endoplasmic reticulum; endoplasmic reticulum membrane; and integral component of membrane. Is expressed in several structures, including head; mesoderm; neural plate; pleuroperitoneal region; and presumptive neural plate. Used to study holoprosencephaly. Orthologous to human CYP26A1 (cytochrome P450 family 26 subfamily A member 1).
Genome Resources
Note
None
Expression
All Expression Data
87 figures from 55 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 7 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cyp26a1 Human Ortholog
No data available
Associated With cyp26a1 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017972 Cytochrome P450, conserved site
Family IPR001128 Cytochrome P450
Family IPR002401 Cytochrome P450, E-class, group I
Homologous_superfamily IPR036396 Cytochrome P450 superfamily
Domain Details Per Protein
Protein Length Cytochrome P450 Cytochrome P450, conserved site Cytochrome P450, E-class, group I Cytochrome P450 superfamily
UniProtKB:P79739 492
UniProtKB:R4GEH0 256
UniProtKB:Q7SXV4 492
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-cyp26a1 polyclonal IgG Rabbit
  • IHC
AnaSpec
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations