ZFIN Gene: pcdh8

ZFIN ID: ZDB-GENE-980526-242

ZFIN ID: ZDB-GENE-980526-242

Gene Name:

protocadherin 8

Gene Symbol:

pcdh8

Sequence Ontology ID :

SO:0000704

Previous Names:

papc (1), paraxial protocadherin (1), sb:eu375, zPAPC

Location:

Chr: 9 Mapping Details/Browsers

Nomenclature History

AUTOMATED DESCRIPTION

Predicted to have calcium ion binding activity; predicted to be involved in cell adhesion; predicted to localize to the integral component of plasma membrane; orthologous to human PCDH8 ...

GENE EXPRESSION
All Expression Data:	92 figures from 72 publications
Directly Submitted Expression Data:	7 figures (17 images) from Thisse et al., 2005 [eu375]
Wild-type Stages, Structures:	Blastula:30%-epiboly (4.66h-5.25h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
	adaxial cell axial mesoderm caudal fin epiblast hypoblast lateral mesoderm margin presumptive mesoderm margin ventro-lateral region margin mesoderm paraxial mesoderm presumptive mesoderm presumptive paraxial mesoderm retina retinal photoreceptor layer segmental plate somite tail bud myoblast tail bud unspecified whole organism dorsal region whole organism posterior region
Curated Microarray Expression:	GEO (1)

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
sa21612	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)

Targeting reagents:

MO1-pcdh8 (1)
MO2-pcdh8 (1)

PHENOTYPE

Data:	Fig. 1 from Skouloudaki et al., 2009
Observed in:	pronephros

DISEASE ASSOCIATED WITH pcdh8 HUMAN ORTHOLOG No data available

DISEASE ASSOCIATED WITH pcdh8 VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	cell adhesion (more)
Cellular Component	integral component of membrane (more)
Molecular Function	calcium ion binding (more)

GO Terms (all 9)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR002126 (1) InterPro:IPR013164 (1) InterPro:IPR015919 (1) InterPro:IPR020894 (1)	PROSITE:PS00232 (1)	Pfam:PF00028 (1) Pfam:PF08266 (1)

TRANSCRIPTS No data available

GENE PRODUCT DESCRIPTION No description available

INTERACTIONS AND PATHWAYS

ANTIBODIESNo data available

PLASMIDS

Addgene

CONSTRUCTS WITH SEQUENCES FROM pcdh8 No data available

MARKER RELATIONSHIPS

pcdh8Contains:	[SNP] rs3728249 (1), rs3728250 (1)
pcdh8Encodes:	[EST] eu375 (1)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_131209 (1)	3137bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CABZ01084081 (1)	42301bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:F1REQ8 (1)	950aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast
Sequence Clusters	UniGene:75833 (1)

Sequence Information (all 12)

OTHER pcdh8 GENE PAGES

Alliance (1)

Gene:30456 (1)

Ensembl(GRCz11):ENSDARG00000006467 (2)

ORTHOLOGY for pcdh8 (Chr: 9)

CITATIONS (138)

{{control.fieldName}} Edit

Attributions

Add new Alias

Attributions for Alias: {{control.newAlias}}

Delete Alias: