FIGURE

Fig. 2

ID

ZDB-FIG-150629-11

Publication

Nagendran et al., 2015 - Canonical Wnt signalling regulates epithelial patterning by modulating levels of laminins in zebrafish appendages

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

Gain of Wnt signalling results in acquisition of stretched cell morphology in the median fin fold. Bright-field images of wild-type sibling (A), apc mutant (B), DMSO- (C) and 0.5 mM BIO-treated (D) embryos. (E-H′) β-Catenin-DAPI overlays (E-H) and β-catenin staining (E′-H′) in given genetic backgrounds and treatments. (I-L) E-cadherin staining in wild-type siblings (I), apc mutant (J), DMSO control (K) and BIO-treated (L) embryos. (M,N) Comparison of epithelial cell aspect ratio plots between sibling and apc mutant (M) as well as between DMSO and BIO-treated embryos (N). Scale bars: 0.1mm in A-D; 10 μm in E-L.

Expression Data

Antibodies:	Ab1-ctnnb Ab2-cdh1
Fish:	TU apc^zf134/zf134
Condition:	chemical treatment: 6-bromoindirubin-3'-oxime
Anatomical Terms:	epidermal basal stratum cell-cell junction epidermal basal stratum nucleus median fin fold epidermal basal stratum
Stage Range:	Prim-15 to Prim-25

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	TU apc^zf134/zf134
Condition:	chemical treatment: 6-bromoindirubin-3'-oxime
Observed In:	embryonic medial fin morphogenesis epidermal basal stratum epidermal basal stratum canonical Wnt signaling pathway epidermal basal stratum ecto-epithelial cell epidermal basal stratum epithelial cell morphogenesis
Stage Range:	Prim-15 to Prim-25

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development