ZFIN ID: ZDB-FIG-150629-12
Nagendran et al., 2015 - Canonical Wnt signalling regulates epithelial patterning by modulating levels of laminins in zebrafish appendages. Development (Cambridge, England)   142(2):320-30 Full text @ Development
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Antibody:
Fish:
Conditions:
Anatomical Terms:
Stage: Prim-5
PHENOTYPE:
Fish:
Conditions:
Observed In:
Stage: Prim-5

Fig. 3 Loss of Wnt signalling results in polygonal morphology throughout the median fin epithelium. (A-D′) β-Catenin-DAPI overlays (A-D) and β-catenin staining (A′-D′) in DMSO- (A,A′), IWR-treated (B,B′), heat-shock control (C,C′) and HS:dkk1-GFP embryos (D,D′) at 24 hpf. (E,F) Comparison of aspect ratios between DMSO and IWR-treated (E), and heat-shock control and HS:dkk1-GFP embryos (F). Scale bar: 10 μm.

Gene Expression Details No data available
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-ctnnb IHC TU control Prim-5 epidermal basal stratum cell-cell junction
IHC Prim-5 epidermal basal stratum nucleus
IHC Prim-5 median fin fold epidermal basal stratum
IHC TU chemical treatment: IWR-1-endo Prim-5 epidermal basal stratum cell-cell junction
IHC Prim-5 median fin fold epidermal basal stratum
IHC TU heat shock Prim-5 epidermal basal stratum cell-cell junction
IHC Prim-5 epidermal basal stratum nucleus
IHC Prim-5 median fin fold epidermal basal stratum
IHC w32Tg heat shock Prim-5 epidermal basal stratum cell-cell junction
IHC Prim-5 median fin fold epidermal basal stratum
Phenotype Details
Fish Conditions Stage Phenotype
TU chemical treatment: IWR-1-endo Prim-5 embryonic medial fin morphogenesis decreased process quality, abnormal
Prim-5 epidermal basal stratum canonical Wnt signaling pathway decreased process quality, abnormal
Prim-5 epidermal basal stratum ecto-epithelial cell oblong, abnormal
Prim-5 epidermal basal stratum epithelial cell morphogenesis decreased process quality, abnormal
w32Tg heat shock Prim-5 embryonic medial fin morphogenesis decreased process quality, abnormal
Prim-5 epidermal basal stratum canonical Wnt signaling pathway decreased process quality, abnormal
Prim-5 epidermal basal stratum ecto-epithelial cell oblong, abnormal
Prim-5 epidermal basal stratum epithelial cell morphogenesis decreased process quality, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development