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ZFIN ID: ZDB-FIG-131213-50
Warga et al., 2013 - Zebrafish Tbx16 regulates intermediate mesoderm cell fate by attenuating Fgf activity. Developmental Biology   383(1):75-89 Full text @ Dev. Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage: 20-25 somites
PHENOTYPE:
Fish:
Observed In:
Stage: 20-25 somites

Fig. 1 spt mutants have less of all types of blood. (A–F) Expression in the intermediate cell mass at 19–20 h of: (A) tal1 and (B) drl in all blood cells; (C) gata1 and (D) hbbe2 in red blood cells; (E) spi1 in white blood cells; and (F) mpx in neutrophils. (G) lcp expression at 19 h in macrophages derived from the head blood island. Embryos are shown from a (A–F) left side view, or (G) dorsal view with anterior to the left. Arrows designate single cells.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
drl WT standard conditions 20-25 somites intermediate cell mass of mesoderm ISH
tbx16b104/b104 standard conditions 20-25 somites intermediate cell mass of mesoderm ISH
gata1a WT standard conditions 20-25 somites nucleate erythrocyte ISH
tbx16b104/b104 standard conditions 20-25 somites nucleate erythrocyte ISH
hbbe2 WT standard conditions 20-25 somites nucleate erythrocyte ISH
tbx16b104/b104 standard conditions 20-25 somites nucleate erythrocyte ISH
lcp1 WT standard conditions 20-25 somites macrophage ISH
tbx16b104/b104 standard conditions 20-25 somites macrophage ISH
mpx WT standard conditions 20-25 somites leukocyte ISH
tbx16b104/b104 standard conditions 20-25 somites leukocyte ISH
spi1b WT standard conditions 20-25 somites leukocyte ISH
tbx16b104/b104 standard conditions 20-25 somites leukocyte ISH
tal1 WT standard conditions 20-25 somites intermediate cell mass of mesoderm ISH
tbx16b104/b104 standard conditions 20-25 somites intermediate cell mass of mesoderm ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
tbx16b104/b104 standard conditions 20-25 somites blood cell decreased amount, abnormal
20-25 somites leukocyte decreased amount, abnormal
20-25 somites macrophage decreased amount, abnormal
20-25 somites nucleate erythrocyte decreased amount, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Developmental Biology for permission to reproduce figures from this article. Please note that this material may be protected by copyright.

Reprinted from Developmental Biology, 383(1), Warga, R.M., Mueller, R.L., Ho, R.K., and Kane, D.A., Zebrafish Tbx16 regulates intermediate mesoderm cell fate by attenuating Fgf activity, 75-89, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.