Gene

lcp1

ID
ZDB-GENE-991213-5
Name
lymphocyte cytosolic protein 1 (L-plastin)
Symbol
lcp1 Nomenclature History
Previous Names
  • cb245 (1)
  • fj24b12
  • l plastin
  • L-plastin (1)
  • leucocyte-specific plastin
  • wu:fj24b12
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity. Predicted to be involved in actin filament bundle assembly and actin filament network formation. Localizes to cytoplasm. Is expressed in several structures, including eye; hematopoietic cell; hematopoietic system; mesoderm; and renal system. Orthologous to human LCP1 (lymphocyte cytosolic protein 1).
Genome Resources
Note
None
Expression
All Expression Data
196 figures from 146 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Kell et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lcp1 Human Ortholog
No data available
Associated With lcp1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR018247 EF-Hand 1, calcium-binding site
Conserved_site IPR001589 Actinin-type actin-binding domain, conserved site
Domain IPR001715 Calponin homology domain
Domain IPR002048 EF-hand domain
Family IPR039956 Plastin-2/3
Family IPR039959 Fimbrin/Plastin
Homologous_superfamily IPR011992 EF-hand domain pair
Homologous_superfamily IPR036872 CH domain superfamily
Domain Details Per Protein
Protein Length Actinin-type actin-binding domain, conserved site Calponin homology domain CH domain superfamily EF-Hand 1, calcium-binding site EF-hand domain EF-hand domain pair Fimbrin/Plastin Plastin-2/3
UniProtKB:Q6P698 624
UniProtKB:A0A140LGK1 624
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab3-lcp1 polyclonal Rabbit
  • IHC
8
Ab5-lcp1 polyclonal IgG Rabbit
  • IHC
GeneTex
3
Ab2-lcp1 polyclonal Rabbit
  • IHC
  • WB
39
Ab1-lcp1 polyclonal Rabbit
  • IHC
20
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations