ZFIN ID: ZDB-FIG-111028-38
Dalgin et al., 2011 - Zebrafish mnx1 controls cell fate choice in the developing endocrine pancreas. Development (Cambridge, England)   138(21):4597-4608 Full text @ Development
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Knockdown Reagents:
Anatomical Term:
Stage: Prim-5
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage: Prim-5

Fig. S6 Mnx1-deficient embryos have expanded expression of the arx alpha cell marker. (A-D) Whole-mount in situ hybridization for arx; fluorescent images of chromogenic in situ hybridizations. Ventral view of 24 hpf (A) uninjected control, (B) control MO-injected, (C) Mnx1 MO1-injected and (D) Mnx1 MO2-injected embryos. Anterior to left. (E) Mean (± s.d.) number of arx-expressing cells. *, P<0.001 (t-test, two-tailed distribution, Bonferroni correction), from a minimum of 11 embryos per group.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
arxa AB control Prim-5 posterior pancreatic bud pancreatic A cell ISH
AB + MO1-mnx1 standard conditions Prim-5 posterior pancreatic bud pancreatic A cell ISH
AB + MO2-mnx1 standard conditions Prim-5 posterior pancreatic bud pancreatic A cell ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
AB + MO1-mnx1 standard conditions Prim-5 pancreatic A cell differentiation increased occurrence, abnormal
Prim-5 posterior pancreatic bud has extra parts of type pancreatic A cell, abnormal
AB + MO2-mnx1 standard conditions Prim-5 pancreatic A cell differentiation increased occurrence, abnormal
Prim-5 posterior pancreatic bud has extra parts of type pancreatic A cell, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development