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General Information
ZIRC
ZFIN ID: ZDB-FIG-110421-14
Zhao et al., 2010 - Interruption of cenph causes mitotic failure and embryonic death and its haploinsufficiency suppresses cancer in zebrafish. The Journal of biological chemistry   285(36):27924-27934 Full text @ J. Biol. Chem.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Term:
Stage Range: 20-25 somites to Prim-15
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage Range: Prim-15 to Long-pec

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
bbc3 WT standard conditions 20-25 somites whole organism RTPCR
Prim-5 whole organism RTPCR
Prim-15 whole organism RTPCR
cenphtsu055Gt/tsu055Gt standard conditions 20-25 somites whole organism RTPCR
Prim-5 whole organism RTPCR
Prim-15 whole organism RTPCR
casp8 WT standard conditions 20-25 somites whole organism RTPCR
Prim-5 whole organism RTPCR
Prim-15 whole organism RTPCR
cenphtsu055Gt/tsu055Gt standard conditions 20-25 somites whole organism RTPCR
Prim-5 whole organism RTPCR
Prim-15 whole organism RTPCR
ccnb1 WT standard conditions 20-25 somites whole organism RTPCR
Prim-5 whole organism RTPCR
Prim-15 whole organism RTPCR
cenphtsu055Gt/tsu055Gt standard conditions 20-25 somites whole organism RTPCR
Prim-5 whole organism RTPCR
Prim-15 whole organism RTPCR
ccne2 WT standard conditions 20-25 somites whole organism RTPCR
Prim-5 whole organism RTPCR
Prim-15 whole organism RTPCR
cenphtsu055Gt/tsu055Gt standard conditions 20-25 somites whole organism RTPCR
Prim-5 whole organism RTPCR
Prim-15 whole organism RTPCR
cdkn1ca WT standard conditions 20-25 somites whole organism RTPCR
Prim-5 whole organism RTPCR
Prim-15 whole organism RTPCR
cenphtsu055Gt/tsu055Gt standard conditions 20-25 somites whole organism RTPCR
Prim-5 whole organism RTPCR
Prim-15 whole organism RTPCR
fadd WT standard conditions 20-25 somites whole organism RTPCR
Prim-5 whole organism RTPCR
Prim-15 whole organism RTPCR
cenphtsu055Gt/tsu055Gt standard conditions 20-25 somites whole organism RTPCR
Prim-5 whole organism RTPCR
Prim-15 whole organism RTPCR
fsta WT standard conditions 20-25 somites whole organism RTPCR
Prim-5 whole organism RTPCR
Prim-15 whole organism RTPCR
cenphtsu055Gt/tsu055Gt standard conditions 20-25 somites whole organism RTPCR
Prim-5 whole organism RTPCR
Prim-15 whole organism RTPCR
gadd45aa WT standard conditions 20-25 somites whole organism RTPCR
Prim-5 whole organism RTPCR
Prim-15 whole organism RTPCR
cenphtsu055Gt/tsu055Gt standard conditions 20-25 somites whole organism RTPCR
Prim-5 whole organism RTPCR
Prim-15 whole organism RTPCR
mdm2 WT standard conditions 20-25 somites whole organism RTPCR
Prim-5 whole organism RTPCR
Prim-15 whole organism RTPCR
cenphtsu055Gt/tsu055Gt standard conditions 20-25 somites whole organism RTPCR
Prim-5 whole organism RTPCR
Prim-15 whole organism RTPCR
tp53 WT standard conditions 20-25 somites whole organism RTPCR
Prim-5 whole organism RTPCR
Prim-15 whole organism RTPCR
cenphtsu055Gt/tsu055Gt standard conditions 20-25 somites whole organism RTPCR
Prim-5 whole organism RTPCR
Prim-15 whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
cenphtsu055Gt/tsu055Gt standard conditions Prim-15 brain apoptotic, abnormal
Prim-15 cysteine-type endopeptidase activity increased rate, abnormal
Prim-15 head apoptotic, abnormal
cenphtsu055Gt/tsu055Gt + MO5-tp53 standard conditions Prim-15 brain apoptotic, abnormal
Prim-15 eye decreased size, abnormal
Prim-15 head apoptotic, abnormal
Prim-15 head opaque, abnormal
Prim-15 spinal cord apoptotic, abnormal
Prim-15 spinal cord opaque, abnormal
Prim-15 trunk curved dorsal, abnormal
Long-pec brain apoptotic, abnormal
Long-pec eye decreased size, abnormal
Long-pec head apoptotic, abnormal
Long-pec head opaque, abnormal
Long-pec spinal cord apoptotic, abnormal
Long-pec spinal cord opaque, abnormal
Long-pec trunk curved dorsal, abnormal
Full text @ J. Biol. Chem.