ZFIN ID: ZDB-GENE-040123-1
Gene Name: cyclin-dependent kinase inhibitor 1Ca
Gene Symbol: cdkn1ca
Sequence Ontology ID : SO:0000704

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Previous Names: cb961 (1), cdkn1c, p21-like (1), p27Xic1-a (1), p57kip2 (1), zgc:86618

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have cyclin-dependent protein serine/threonine kinase inhibitor activity and kinase activity; involved in cell fate specification, glial cell differentiation, and negative regulation of  ...
GENE EXPRESSION
All Expression Data: 42 figures from 29 publications
Directly Submitted Expression Data: 6 figures (17 images) from Thisse et al., 2001 [cb961]
Wild-type Stages, Structures: Cleavage:16-cell (1.5h-1.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa38636 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 2 figures from Osborn et al., 2011
    Observed in:
    DISEASE ASSOCIATED WITH cdkn1ca HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Beckwith-Wiedemann syndrome Beckwith-Wiedemann syndrome 130650
    IMAGe syndrome IMAGE syndrome 614732
    DISEASE ASSOCIATED WITH cdkn1ca VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell fate specification (more)
    Cellular Component nucleus (more)
    Molecular Function cyclin-dependent protein serine/threonine kinase inhibitor activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003175 (1)
  • Pfam:PF02234 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cdkn1ca-201 (1) 1566
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM cdkn1ca
    MARKER RELATIONSHIPS
    cdkn1caContained in: [BAC] DKEY-7P8 (1) (order this)
    cdkn1caEncodes: [EST] cb961 (1) (order this)
    [cDNA] MGC:86618 (1) (order this), MGC:173881 (1) (order this)
    cdkn1caIs Hybridized by: [STS] chunp487
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002040 (1) 1199bp
    Genomic GenBank:AL928843 (1) 179577bp
    Select Tool
    Polypeptide UniProtKB:Q6IQT7 (1) 212aa
    Sequence Clusters UniGene:76099 (1)
    Sequence Information (all 15)
    OTHER cdkn1ca GENE PAGES
  • Alliance (1)
  • Gene:399483 (1)
  • VEGA:OTTDARG00000013085 (1)
  • Ensembl(GRCz11):ENSDARG00000010878 (2)
  • ORTHOLOGY for cdkn1ca (Chr: 7)
    CITATIONS (68)