header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-040426-1501
Gene Name: growth arrest and DNA-damage-inducible, alpha, a
Gene Symbol: gadd45aa    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: gadd45al, zgc:65993, zgc:77480 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Involved in paraxial mesoderm development. Predicted to localize to the cytoplasm and nucleus. Is expressed in several structures, including endoderm; eye; intestine; otic placode; and solid lens vesicle. Orthologous to human GADD45A (growth arrest and DNA damage inducible alpha).
Genome Resources: Alliance (1),  Gene:393548 (1),  Ensembl(GRCz11):ENSDARG00000043581 (2)
GENE EXPRESSION
All Expression Data: 24 figures from 16 publications
Directly Submitted Expression Data: 6 figures (8 images) from Thisse et al., 2004 [MGC:65993]
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la023410Tg Transgenic Insertion Unknown Unknown DNA
sa1122 Point Mutation Unknown Premature Stop ENU
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-gadd45aa N/A 2
MO2-gadd45aa N/A 1
MO3-gadd45aa N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH gadd45aa HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH gadd45aa VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process paraxial mesoderm development (more)
Cellular Component nucleus (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004038 (1)
  • InterPro:IPR024824 (1)
  • InterPro:IPR029064 (1)
  • Pfam:PF01248 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gadd45aa-201 (1)    Ensembl 1253
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gadd45aa No data available
    MARKER RELATIONSHIPS
    gadd45aa Contained in: [BAC] DKEY-171B9 (1) (order this)
    gadd45aa Encodes: [cDNA] MGC:65993 (1) (order this), MGC:77480 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200576 (1) 1240 bp
    Genomic GenBank:CU693482 (1) 76766 bp
    Select Tool
    Polypeptide UniProtKB:F1R8Z0 (1) 157 aa
    Sequence Clusters UniGene:27107 (1)
    Sequence Information (all 17)
    ORTHOLOGY for gadd45aa ( Chr: 2 )
    CITATIONS (63)