Gene

bbc3

ID
ZDB-GENE-070119-4
Name
BCL2 binding component 3
Symbol
bbc3 Nomenclature History
Previous Names
  • Puma (1)
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Involved in cellular response to ionizing radiation; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process. Predicted to localize to mitochondrion. Is expressed in several structures, including central nervous system; head; heart; male organism; and pleuroperitoneal region. Orthologous to human BBC3 (BCL2 binding component 3).
Genome Resources
Note
None
Expression
All Expression Data
29 figures from 26 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bbc3 Human Ortholog
No data available
Associated With bbc3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR031661 Bcl-2-binding component 3
Domain Details Per Protein
Protein Length Bcl-2-binding component 3
UniProtKB:Q0GKC9 181
UniProtKB:F1QKA1 181
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations