Gene
fadd
- ID
- ZDB-GENE-070606-3
- Name
- Fas (tnfrsf6)-associated via death domain
- Symbol
- fadd Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have caspase binding activity and death receptor binding activity. Involved in positive regulation of apoptotic process. Predicted to localize to CD95 death-inducing signaling complex and cytoplasm. Human ortholog(s) of this gene implicated in leukemia. Is expressed in several structures, including axis; brain; germ ring; immature eye; and ventral mandibular arch. Orthologous to human FADD (Fas associated via death domain).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Serbanovic-Canic et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Immunodeficiency 90 with encephalopathy, functional hyposplenia, and hepatic dysfunction | 613759 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available