FIGURE

Fig. S5

ID

ZDB-FIG-110224-19

Publication

Dal-Pra et al., 2011 - FoxA transcription factors are essential for the development of dorsal axial structures

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Fig. S5

Phenotype of floating head morphant. (A and B) Embryos injected with 1.6 ng MO-Flh do not develop notochord and hypochord and present a patchy floor plate and fused somites at 24 hpf. (B) High magnification of the trunk region of Flh morphants. (C–F) Analysis of twist2 (C and D) and myf5 (E and F) expression at 80% epiboly. In Flh morphants, twist2 expression domain is narrower (D) and myf5 territory is partially fused along the dorsal midline (F). (G–J) At shield stage, expressions of foxA2 (G and H) and foxA3 (I and J) are not affected in Flh morphants (H and J) compared to wild-type (G and I). (A and B) Lateral views, anterior to the left. (C–F) Dorsal views, anterior up. (G–J) Animal pole views.

Expression Data

Genes:	foxa2 foxa3 myf5 twist2
Fish:	WT WT + MO2-noto
Knockdown Reagent:	MO2-noto
Anatomical Terms:	axial chorda mesoderm hypoblast presumptive paraxial mesoderm
Stage Range:	Shield to 75%-epiboly

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO2-noto
Knockdown Reagent:	MO2-noto
Observed In:	axial chorda mesoderm floor plate hypochord notochord paraxial mesoderm paraxial mesoderm left side paraxial mesoderm right side shield somite
Stage Range:	Shield to Prim-5

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 350(2), Dal-Pra, S., Thisse, C., and Thisse, B., FoxA transcription factors are essential for the development of dorsal axial structures, 484-495, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.