ZFIN ID: ZDB-FIG-100603-3
Zuniga et al., 2010 - Jagged-Notch signaling ensures dorsal skeletal identity in the vertebrate face. Development (Cambridge, England)   137(11):1843-1852 Full text @ Development
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Anatomical Terms:
Stage: Prim-25

Fig. 3 Jag1b generally represses ventral gene expression in the pharyngeal arches. (A-U) In situ hybridizations showing the mandibular and hyoid arch expression of dlx6a (A-C), epha4b (D-F), msxe (G-I), hand2 (M-O), ednra2 (P-R) and edn1 (S-U) at 36 hpf and of bapx1 (J-L) at 40 hpf. The expression of dlx6a, epha4b, msxe and bapx1 is dorsally expanded in jag1bb1105 zebrafish embryos (B,E,H,K) and is greatly reduced in 20-28 hpf heat shock-treated hsp70I:Gal4; UAS:JAG1 embryos (C,F,I,L). hand2 expression is reduced in UAS:JAG1 embryos, whereas ednra2 and edn1 expression is unaffected in jag1bb1105 and UAS:JAG1 embryos. Endodermal pouches are outlined.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
dlx6a WT standard conditions Prim-25 mandibular arch skeleton ISH
Prim-25 pharyngeal arch 2 skeleton ISH
el108Tg; kca4Tg/+ heat shock Prim-25 mandibular arch skeleton ISH
Prim-25 pharyngeal arch 2 skeleton ISH
jag1bb1105/b1105 standard conditions Prim-25 mandibular arch skeleton ISH
Prim-25 pharyngeal arch 2 skeleton ISH
edn1 WT standard conditions Prim-25 mandibular arch skeleton ISH
Prim-25 pharyngeal arch 2 skeleton ISH
el108Tg; kca4Tg/+ heat shock Prim-25 mandibular arch skeleton ISH
Prim-25 pharyngeal arch 2 skeleton ISH
jag1bb1105/b1105 standard conditions Prim-25 mandibular arch skeleton ISH
Prim-25 pharyngeal arch 2 skeleton ISH
ednraa WT standard conditions Prim-25 mandibular arch skeleton ISH
Prim-25 pharyngeal arch 2 skeleton ISH
el108Tg; kca4Tg/+ heat shock Prim-25 mandibular arch skeleton ISH
Prim-25 pharyngeal arch 2 skeleton ISH
jag1bb1105/b1105 standard conditions Prim-25 mandibular arch skeleton ISH
Prim-25 pharyngeal arch 2 skeleton ISH
epha4b WT standard conditions Prim-25 mandibular arch skeleton ISH
Prim-25 pharyngeal arch 2 skeleton ISH
el108Tg; kca4Tg/+ heat shock Prim-25 mandibular arch skeleton ISH
Prim-25 pharyngeal arch 2 skeleton ISH
jag1bb1105/b1105 standard conditions Prim-25 mandibular arch skeleton ISH
Prim-25 pharyngeal arch 2 skeleton ISH
hand2 WT standard conditions Prim-25 mandibular arch skeleton ISH
Prim-25 pharyngeal arch 2 skeleton ISH
el108Tg; kca4Tg/+ heat shock Prim-25 mandibular arch skeleton ISH
Prim-25 pharyngeal arch 2 skeleton ISH
jag1bb1105/b1105 standard conditions Prim-25 mandibular arch skeleton ISH
Prim-25 pharyngeal arch 2 skeleton ISH
msx1a WT standard conditions Prim-25 mandibular arch skeleton ISH
Prim-25 pharyngeal arch 2 skeleton ISH
el108Tg; kca4Tg/+ heat shock Prim-25 mandibular arch skeleton ISH
Prim-25 pharyngeal arch 2 skeleton ISH
jag1bb1105/b1105 standard conditions Prim-25 mandibular arch skeleton ISH
Prim-25 pharyngeal arch 2 skeleton ISH
nkx3-2 WT standard conditions Prim-25 mandibular arch skeleton ISH
Prim-25 pharyngeal arch 2 skeleton ISH
el108Tg; kca4Tg/+ heat shock Prim-25 mandibular arch skeleton ISH
Prim-25 pharyngeal arch 2 skeleton ISH
jag1bb1105/b1105 standard conditions Prim-25 mandibular arch skeleton ISH
Prim-25 pharyngeal arch 2 skeleton ISH
Antibody Labeling Details No data available
Phenotype Details No data available
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development