FIGURE

Fig. 3

ID

ZDB-FIG-100603-3

Publication

Zuniga et al., 2010 - Jagged-Notch signaling ensures dorsal skeletal identity in the vertebrate face

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Fig. 3

Jag1b generally represses ventral gene expression in the pharyngeal arches. (A-U) In situ hybridizations showing the mandibular and hyoid arch expression of dlx6a (A-C), epha4b (D-F), msxe (G-I), hand2 (M-O), ednra2 (P-R) and edn1 (S-U) at 36 hpf and of bapx1 (J-L) at 40 hpf. The expression of dlx6a, epha4b, msxe and bapx1 is dorsally expanded in jag1b^b1105 zebrafish embryos (B,E,H,K) and is greatly reduced in 20-28 hpf heat shock-treated hsp70I:Gal4; UAS:JAG1 embryos (C,F,I,L). hand2 expression is reduced in UAS:JAG1 embryos, whereas ednra2 and edn1 expression is unaffected in jag1b^b1105 and UAS:JAG1 embryos. Endodermal pouches are outlined.

Expression Data

Genes:	dlx6a edn1 ednraa epha4b hand2 msx1a nkx3-2
Fish:	WT jag1b^b1105/b1105 el108Tg; kca4Tg/+
Condition:	heat shock
Anatomical Terms:	mandibular arch skeleton pharyngeal arch 2 skeleton
Stage:	Prim-25

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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