ZFIN is now using GRCz12tu for Genomic Data
Gene
ednraa
- ID
- ZDB-GENE-010906-2
- Name
- endothelin receptor type Aa
- Symbol
- ednraa Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable endothelin receptor activity. Acts upstream of with a positive effect on developmental pigmentation. Acts upstream of or within cartilage development; regulation of proton transport; and social behavior. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including epithelium; forebrain; neural crest; pharyngeal arch; and vasculature. Human ortholog(s) of this gene implicated in hypertension (multiple); lung disease; mandibulofacial dysostosis with alopecia; migraine; and obstructive sleep apnea. Orthologous to human EDNRA (endothelin receptor type A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 20 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Endothelin receptor A | Endothelin receptor family | GPCR, rhodopsin-like, 7TM | G-protein coupled endothelin receptor | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|---|---|---|
| UniProtKB:B3DLG5 | InterPro | 422 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ednraa-201
(1)
|
Ensembl | 2,665 nt | ||
| mRNA |
ednraa-203
(1)
|
Ensembl | 200 nt | ||
| mRNA |
ednraa-204
(1)
|
Ensembl | 1,656 nt | ||
| mRNA |
ednraa-205
(1)
|
Ensembl | 1,690 nt | ||
| mRNA |
ednraa-206
(1)
|
Ensembl | 1,436 nt | ||
| mRNA |
ednraa-207
(1)
|
Ensembl | 1,236 nt | ||
| ncRNA |
ednraa-003
(1)
|
Ensembl | 391 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers