Gene

ednraa

ID
ZDB-GENE-010906-2
Name
endothelin receptor type Aa
Symbol
ednraa Nomenclature History
Previous Names
  • Ednra2 (1)
  • ednra
  • etID40953.1 (1)
  • parade (1)
  • pde
  • wu:fb75g12
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have endothelin receptor activity. Involved in cartilage development; developmental pigmentation; and regulation of proton transport. Predicted to localize to integral component of membrane. Is expressed in epithelium; gill; neural crest; pharyngeal arch; and vasculature. Human ortholog(s) of this gene implicated in hypertension (multiple); lung disease; mandibulofacial dysostosis with alopecia; migraine; and obstructive sleep apnea. Orthologous to human EDNRA (endothelin receptor type A).
Genome Resources
Note
None
Expression
All Expression Data
10 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
20 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ednraa Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
mandibulofacial dysostosis with alopecia Alliance Mandibulofacial dysostosis with alopecia 616367
migraine Alliance {Migraine, resistance to} 157300
Associated With ednraa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR000499 Endothelin receptor family
Family IPR002175 Endothelin receptor A
Domain Details Per Protein
Protein Length Endothelin receptor A Endothelin receptor family GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like
UniProtKB:B3DLG5 422
UniProtKB:Q90YB8 168
UniProtKB:B3DGY2 422
UniProtKB:B8JIH1 24
UniProtKB:D0MQ51 411
UniProtKB:A5JV23 422
UniProtKB:A0A0B5JFE8 93
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations