Gene
hand2
- ID
- ZDB-GENE-000511-1
- Name
- heart and neural crest derivatives expressed 2
- Symbol
- hand2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have DNA binding activity and protein dimerization activity. Involved in several processes, including animal organ development; determination of intestine left/right asymmetry; and nervous system development. Predicted to localize to nucleus. Is expressed in several structures, including cardiovascular system; digestive system; head; mesoderm; and pectoral fin. Orthologous to human HAND2 (heart and neural crest derivatives expressed 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 172 figures from 119 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu107 (17 images)
- eu880 (13 images)
- IMAGE:7165464 (20 images)
Wild Type Expression Summary
- All Phenotype Data
- 17 figures from 11 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | E-box Binding Transcriptional Regulators | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain |
|---|---|---|---|---|
|
UniProtKB:A2BDM6
|
205 | |||
|
UniProtKB:P57102
|
208 |
Interactions and Pathways
No data available
Plasmids
No data available