Gene
edn1
- ID
- ZDB-GENE-000920-1
- Name
- endothelin 1
- Symbol
- edn1 Nomenclature History
- Previous Names
-
- et-1
- et1
- fb14d01
- suc
- sucker
- wu:fb14d01 (1)
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Involved in several processes, including anterior lateral line neuromast development; face morphogenesis; and skeletal system development. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); bronchial disease (multiple); obesity; obstructive sleep apnea; and rheumatoid arthritis. Is expressed in several structures, including cardiovascular system; ectoderm; mesoderm; neural crest; and pharyngeal arch. Orthologous to human EDN1 (endothelin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 54 figures from 34 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu115 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- 43 figures from 22 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Endothelin | Endothelin-like toxin | Endothelin-like toxin, conserved site |
|---|---|---|---|---|
|
UniProtKB:Q9I8G3
|
188 |
Interactions and Pathways
Plasmids
No data available