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ZIRC
ZFIN ID: ZDB-GENE-000920-1
Gene Name: endothelin 1
Gene Symbol: edn1
Sequence Ontology ID : SO:0000704

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Previous Names: et-1, et1, fb14d01, suc, sucker, wu:fb14d01 (1)

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(Including Attributions)
Location: Chr: 19 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Involved in animal organ development; dorsal/ventral pattern formation; and face morphogenesis. Predicted to localize to the extracellular region. Human ortholog(s) of this gene implicated in several  ...
GENE EXPRESSION
All Expression Data: 51 figures from 32 publications
Directly Submitted Expression Data: 6 figures (12 images) from Thisse et al., 2005 [eu115]
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
tf216b Point Mutation Unknown Missense ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 40 figures from 21 publications
    Observed in:
    DISEASE ASSOCIATED WITH edn1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    {High density lipoprotein cholesterol level QTL 7}
    Question mark ears, isolated 612798
    Auriculocondylar syndrome 3 615706
    DISEASE ASSOCIATED WITH edn1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cartilage development (more)
    Cellular Component extracellular region (more)
    GO Terms (all 13)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA edn1-201 (1) 1220
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    MARKER RELATIONSHIPS
    edn1Contained in: [BAC] DKEY-31K9 (1) (order this)
    edn1Encodes: [EST] eu115 (1), fb14d01 (1)
    [cDNA] MGC:193745 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131519 (1) 1224bp
    Genomic GenBank:CT573165 (1) 70864bp
    Select Tool
    Polypeptide UniProtKB:A5WW41 (1) 188aa
    Sequence Clusters UniGene:4076 (1)
    Sequence Information (all 15)
    ORTHOLOGY for edn1 (Chr: 19)
    CITATIONS (92)