ZFIN ID: ZDB-FIG-070307-70
Hans et al., 2007 - Fgf-dependent otic induction requires competence provided by Foxi1 and Dlx3b. BMC Developmental Biology   7(1):5 Full text @ BMC Dev. Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Anatomical Term:
Stage: Bud

Fig. 2 Ectopic Fgf-signaling represses foxi1 and dlx3b before and during gastrulation. (A, B, F, G) Expression of foxi1 and dlx3b is absent after overexpression of fgf8 by mRNA injections at the 1-cell stage in comparison to wild-type embryos. (C, D, H, I) Misexpression of fgf8 at 30% epiboly or shield stages results in smaller foxi1 and dlx3b expression domains. (E, J) Loss of Fgf-signaling after pharmacological inhibition with SU5402 from late blastula stages until the end of gastrulation has no effect on the ventral expression of foxi1 and dlx3b. Lateral views at the end of gastrulation with dorsal to the right and anterior towards the top. Scale bar: 100 μm.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
dlx3b WT standard conditions Bud ectoderm ISH
WT chemical treatment: SU5402 Bud ectoderm ISH
foxi1 WT standard conditions Bud ectoderm ISH
WT chemical treatment: SU5402 Bud ectoderm ISH
Antibody Labeling Details No data available
Phenotype Details No data available
Acknowledgments:
ZFIN wishes to thank the journal BMC Developmental Biology for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ BMC Dev. Biol.