ZFIN ID: ZDB-FIG-070307-72
Hans et al., 2007 - Fgf-dependent otic induction requires competence provided by Foxi1 and Dlx3b. BMC Developmental Biology   7(1):5 Full text @ BMC Dev. Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Anatomical Terms:
Stage: Bud

Fig. 4 foxi1 and vent but not dlx3b are direct targets of Bmp-signaling during gastrulation. (A, B, E, F, I, J) Expression of foxi1, dlx3b and vent is expanded after Bmp2a protein injection at late blastula stages in comparison to wild-type embryos. (C, D, G, H, K, L) Pharmacological inhibition of protein synthesis with cycloheximide (CHX) at late blastula stages blocks all indications of foxi1, dlx3b and vent expression (C, G, K), whereas foxi1 and vent but not dlx3b expression is restored in CHX-treated embryos after Bmp2a protein injection (D, H, L). Lateral views at the end of gastrulation with dorsal to the right and anterior towards the top (note that CHX treatment blocks epiboly movements). Scale bar: 90 μm.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
dlx3b WT standard conditions Bud ectoderm ISH
WT chemical treatment: pharmaceutical Bud Not Detected ectoderm ISH
foxi1 WT standard conditions Bud ectoderm ISH
WT chemical treatment: pharmaceutical Bud Not Detected ectoderm ISH
vent WT standard conditions Bud margin ISH
WT chemical treatment: pharmaceutical Bud Not Detected margin ISH
Antibody Labeling Details No data available
Phenotype Details No data available
Acknowledgments:
ZFIN wishes to thank the journal BMC Developmental Biology for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ BMC Dev. Biol.