ZFIN ID: ZDB-FIG-070307-69
Hans et al., 2007 - Fgf-dependent otic induction requires competence provided by Foxi1 and Dlx3b. BMC Developmental Biology   7(1):5 Full text @ BMC Dev. Biol.
Anatomical Term:
Stage: Prim-5

Fig. 1 Otic vesicle size is affected by the overexpression of fgf8 depending on the developmental stage. (A, B) Overexpression of fgf8 by mRNA injections at the 1-cell stage completely ablates all indications of otic fate (27/40 embryos, B) in comparison to wild-type vesicles (A). (C-E) Misexpression of fgf8 at 30% epiboly (28/28 embryos, C), shield stage (27/28 embryos, D) and 75% epiboly (29/29 embryos, E) results in smaller otic vesicles. (F-H) Otic vesicles are increased in size if fgf8 is misexpressed at the tailbud (26/29 embryos, F) or the 4-somite stage (24/28 embryos, G) whereas at the 8-somite stage no change in vesicle size is observed (26/26 embryos, H). Lateral views of otic vesicles highlighted with starmaker at 24h with anterior to the left and dorsal towards the top. Scale bar: 30 μm.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
stm WT standard conditions Prim-5 otic vesicle ISH
Antibody Labeling Details No data available
Phenotype Details No data available
ZFIN wishes to thank the journal BMC Developmental Biology for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ BMC Dev. Biol.