ZFIN

ZFIN ID: ZDB-GENE-020930-1

ZFIN ID: ZDB-GENE-020930-1

CITATIONS (50 total)

Gene Name:	thyrotropin-releasing hormone
Gene Symbol:	trh

Chen, L., Wang, Y., Giesy, J.P., Chen, F., Shi, T., Chen, J., Xie, P. (2018) Microcystin-LR affects the hypothalamic-pituitary-inter-renal (HPI) axis in early life stages (embryos and larvae) of zebrafish. Environmental pollution (Barking, Essex : 1987). 241:540-548

Dong, X., Xu, H., Wu, X., Yang, L. (2017) Multiple bioanalytical method to reveal developmental biological responses in zebrafish embryos exposed to triclocarban. Chemosphere. 193:251-258

Díaz, M., Becerra, M., Manso, M.J., and Anadón, R. (2002) Distribution of thyrotropin-releasing hormone (TRH) immunoreactivity in the brain of the zebrafish (Danio rerio). The Journal of comparative neurology. 450(1):45-60

Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549

Fernandes, A.M., Beddows, E., Filippi, A., and Driever, W. (2013) Orthopedia Transcription Factor otpa and otpb Paralogous Genes Function during Dopaminergic and Neuroendocrine Cell Specification in Larval Zebrafish. PLoS One. 8(9):e75002

Fernandes, A.M., Fero, K., Arrenberg, A.B., Bergeron, S.A., Driever, W., and Burgess, H.A. (2012) Deep Brain Photoreceptors Control Light-Seeking Behavior in Zebrafish Larvae. Current biology : CB. 22(21):2042-2047

Fuzzen, M.L., Van Der Kraak, G., and Bernier, N.J. (2010) Stirring Up New Ideas About the Regulation of the Hypothalamic-Pituitary-Interrenal Axis in Zebrafish (Danio rerio). Zebrafish. 7(4):349-358

Han, Z., Li, Y., Zhang, S., Song, N., Xu, H., Dang, Y., Liu, C., Giesy, J.P., Yu, H. (2017) Prenatal transfer of decabromodiphenyl ether (BDE-209) results in disruption of the thyroid system and developmental toxicity in zebrafish offspring. Aquatic toxicology (Amsterdam, Netherlands). 190:46-52

Hang, C.Y., Kitahashi, T., Parhar, I.S. (2014) Localization and characterization of val-opsin isoform-expressing cells in the brain of adult zebrafish. The Journal of comparative neurology. 522(17):3847-60

Herget, U., Ryu, S. (2015) Coexpression analysis of nine neuropeptides in the neurosecretory preoptic area of larval zebrafish. Frontiers in Neuroanatomy. 9:2

Herget, U., Wolf, A., Wullimann, M.F., and Ryu, S. (2014) Molecular neuroanatomy and chemoarchitecture of the neurosecretory preoptic-hypothalamic area in zebrafish larvae. The Journal of comparative neurology. 522(7):1542-64

Horstick, E.J., Bayleyen, Y., Sinclair, J.L., Burgess, H.A. (2017) Search strategy is regulated by somatostatin signaling and deep brain photoreceptors in zebrafish. BMC Biology. 15:4

Kwon, B., Kho, Y., Kim, P.G., Ji, K. (2016) Thyroid endocrine disruption in male zebrafish following exposure to binary mixture of bisphenol AF and sulfamethoxazole. Environmental Toxicology and Pharmacology. 48:168-174

Liang, X., Li, J., Martyniuk, C.J., Wang, J., Mao, Y., Lu, H., Zha, J. (2017) Benzotriazole ultraviolet stabilizers alter the expression of the thyroid hormone pathway in zebrafish (Danio rerio) embryos. Chemosphere. 182:22-30

Liang, Y.Q., Huang, G.Y., Ying, G.G., Liu, S.S., Jiang, Y.X., Liu, S. (2015) Progesterone and norgestrel alter transcriptional expression of genes along the hypothalamic-pituitary-thyroid axis in zebrafish embryos-larvae. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 167:101-7

Liu, C., Yu, H., and Zhang, X. (2013) Zebrafish embryos/larvae for rapid determination of effects on hypothalamic-pituitary-thyroid (HPT) and hypothalamic-pituitary-interrenal (HPI) axis: mRNA expression. Chemosphere. 93(10):2327-32

Liu, C., Zhang, X., Deng, J., Hecker, M., Al-Khedhairy, A., Giesy, J.P., and Zhou, B. (2011) Effects of Prochloraz or Propylthiouracil on the Cross-Talk between the HPG, HPA, and HPT Axes in Zebrafish. Environmental science & technology. 45(2):769-775

Liu, J., Merkle, F.T., Gandhi, A.V., Gagnon, J.A., Woods, I.G., Chiu, C.N., Shimogori, T., Schier, A.F., Prober, D.A. (2015) Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9. Development (Cambridge, England). 142(6):1113-24

Liu, X., Jung, D., Jo, A., Ji, K., Moon, H.B., Choi, K. (2016) Long-term exposure to triphenyl phosphate alters hormone balance and HPG, HPI, and HPT gene expression in zebrafish (Danio rerio). Environmental toxicology and chemistry. 35(9):2288-96

Liu, Y., Wu, D., Xu, Q., Yu, L., Liu, C., Wang, J. (2017) Acute exposure to tris (2-butoxyethyl) phosphate (TBOEP) affects growth and development of embryo-larval zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 191:17-24

Löhr, H., Hess, S., Pereira, M.M.A., Reinoß, P., Leibold, S., Schenkel, C., Wunderlich, C.M., Kloppenburg, P., Brüning, J.C., Hammerschmidt, M. (2018) Diet-Induced Growth Is Regulated via Acquired Leptin Resistance and Engages a Pomc-Somatostatin-Growth Hormone Circuit. Cell Reports. 23:1728-1741

Löhr, H., Ryu, S., and Driever, W. (2009) Zebrafish diencephalic A11-related dopaminergic neurons share a conserved transcriptional network with neuroendocrine cell lineages. Development (Cambridge, England). 136(6):1007-1017

Ma, Z., Tang, S., Su, G., Miao, Y., Liu, H., Xie, Y., Giesy, J.P., Saunders, D.M., Hecker, M., Yu, H. (2016) Effects of tris (2-butoxyethyl) phosphate (TBOEP) on endocrine axes during development of early life stages of zebrafish (Danio rerio). Chemosphere. 144:1920-1927

Pandey, S., Shekhar, K., Regev, A., Schier, A.F. (2018) Comprehensive Identification and Spatial Mapping of Habenular Neuronal Types Using Single-Cell RNA-Seq. Current biology : CB. 28(7):1052-1065.e7

Schweitzer, J., Löhr, H., Bonkowsky, J.L., Hübscher, K., and Driever, W. (2013) Sim1a and Arnt2 contribute to hypothalamo-spinal axon guidance by regulating Robo2 activity via a Robo3-dependent mechanism. Development (Cambridge, England). 140(1):93-106

Shi, W.J., Ying, G.G., Huang, G.Y., Liang, Y.Q., Hu, L.X., Zhao, J.L., Zhang, J.N. (2017) Transcriptional and Biochemical Alterations in Zebrafish Eleuthero-Embryos (Danio rerio) After Exposure to Synthetic Progestogen Dydrogesterone. Bulletin of environmental contamination and toxicology. 99(1):39-45

Spikol, E.D., Glasgow, E. (2018) Separate roles for Med12 and Wnt signaling in regulation of oxytocin expression. Biology Open. 7(3)

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

Teng, M., Zhu, W., Wang, D., Yan, J., Qi, S., Song, M., Wang, C. (2018) Acute exposure of zebrafish embryo (Danio rerio) to flutolanil reveals its developmental mechanism of toxicity via disrupting the thyroid system and metabolism. Environmental pollution (Barking, Essex : 1987). 242:1157-1165

Van Camp, K.A., Baggerman, G., Blust, R., Husson, S.J. (2017) Peptidomics of the zebrafish Danio rerio: In search for neuropeptides. Journal of proteomics. 150:290-296

Zada, D., Tovin, A., Lerer-Goldshtein, T., Vatine, G.D., Appelbaum, L. (2014) Altered Behavioral Performance and Live Imaging of Circuit-Specific Neural Deficiencies in a Zebrafish Model for Psychomotor Retardation. PLoS Genetics. 10:e1004615

Zhang, C., Forlano, P.M., and Cone, R.D. (2012) AgRP and POMC neurons are hypophysiotropic and coordinately regulate multiple endocrine axes in a larval teleost. Cell Metabolism. 15(2):256-264

Zhang, S., Guo, X., Lu, S., Sang, N., Li, G., Xie, P., Liu, C., Zhang, L., Xing, Y. (2018) Exposure to PFDoA causes disruption of the hypothalamus-pituitary-thyroid axis in zebrafish larvae. Environmental pollution (Barking, Essex : 1987). 235:974-982

Zheng, X., Zhu, Y., Liu, C., Liu, H., Giesy, J.P., Hecker, M., Lam, M.H., and Yu, H. (2012) Accumulation and Biotransformation of BDE-47 by Zebrafish Larvae and Teratogenicity and Expression of Genes along the Hypothalamus-Pituitary-Thyroid Axis. Environmental science & technology. 46(23):12943-12951

Additional Citations (16):

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

GOA curators, UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. Manually curated data.

UniProt curators (2015) Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features.. Automated Data Submission.

UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. Manually curated data.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

ZFIN Staff (2003) Computational Sequence to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Curation of Protein Database Links. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.