PUBLICATION

Computational Sequence to Gene Association in ZFIN

Authors
ZFIN Staff
ID
ZDB-PUB-031022-5
Date
2003
Source
Semi-automated Curation : (Curation)
Registered Authors
Keywords
none
MeSH Terms
none
PubMed
none
Abstract
A comparison of mRNAs and cDNAs to ESTs is produced each month as part of the Unigene build at NCBI. A candidate set of merges between ESTs and genes existing in ZFIN is provided to ZFIN through a collaboration with LocusLink. Automated EST to gene associations are based on the quality of the sequence similarity match between the target EST sequence and the query transcript sequences in ZFIN. Automated associations of EST sequences require an identity of 99% or higher over 90% of the length of the query sequence. Additional information such as map location and expression data are transferred to the gene. ESTs with a significant identity match (97-98%) over 90% of the length are considered for merges after a curatorial review. To obtain more detailed information about this process or to send comments, please contact ZFIN.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping