Transgenic Construct

Tg(hsp70l:dnfgfr1a-EGFP)

ID

ZDB-TGCONSTRCT-070117-101

Previous Names

Tg(hsp70l:dnfgfr1-EGFP)

Type

engineered_plasmid

Regulatory Regions

hsp70l

Coding Sequences

EGFP (1)
fgfr1a (1)

[Em λ][Ex λ]

Fpbase:EGFP

Contains Sequences

None

Note

This construct contains a dominant-negative fgfr1-egfp fusion gene driven by a heat-inducible zebrafish hsp70 promoter, exhibiting potent inhibitory effects on Fgf signaling. Source: Lee et al. 2005, ZDB-PUB-051031-6

Plasmid Map

None

Genomic Features

That Utilize Tg(hsp70l:dnfgfr1a-EGFP) Construct

Genomic Feature	Affected Genomic Regions
pd1Tg

Transgenics

That Utilize Tg(hsp70l:dnfgfr1a-EGFP) Construct

Fish	Affected Genomic Regions	Phenotype	Gene Expression
aldh1a2^i26/i26; pd1Tg	aldh1a2	Fig. 6 from Cunningham et al., 2013
bns7Tg; pd1Tg		Fig. 6 from Rasouli et al., 2018	Fig. 6 from Rasouli et al., 2018
cz3327Tg; oz5Tg; pd1Tg/pd1Tg		2 figures from Talbot et al., 2019
etsrp^ci32Gt/+; c264Tg; pd1Tg	etsrp	Fig. 6 from Chestnut et al., 2020
foxm1^x67/x67; pd1Tg	foxm1	Fig. 6 from Ali et al., 2025
fr13Tg/+; pd1Tg/+			Fig. 8 from Shin et al., 2007
gbx1^fh271/fh271; gbx2^fh253/fh253; jh1Tg; pd1Tg + MO1-otx2a + MO1-otx2b			Fig. 6 from Su et al., 2014
gbx1^fh271/fh271; gbx2^fh253/fh253; pd1Tg + MO1-otx2a + MO1-otx2b			Fig. 6 from Su et al., 2014
i106Tg; pd1Tg		Fig. 3 from Yin et al., 2018	Fig. 3 from Yin et al., 2018
i233Tg; pd1Tg		Fig. 3 from Yin et al., 2018	Fig. 3 from Yin et al., 2018
jh1Tg; pd1Tg			Fig. 6 from Su et al., 2014
jh1Tg; pd1Tg + MO1-otx2a + MO1-otx2b			Fig. 6 from Su et al., 2014
kca3Tg; kca4Tg; pd1Tg (AB)			Fig. 6 from Lee et al., 2014
la4Tg; pd1Tg/+; zf169Tg		Fig. 1 from Lee et al., 2014	Fig. 1 from Lee et al., 2014
pd1Tg		23 figures from 18 publications	36 figures from 26 publications
pd1Tg + MO1-dmbx1a		Fig. 6 from Wong et al., 2015	Fig. 6 from Wong et al., 2015
pd1Tg + MO1-otx2a + MO1-otx2b			Fig. 6 from Su et al., 2014
pd1Tg + MO4-tfap2a		Fig. 6 from Kantarci et al., 2015	Fig. 6 from Kantarci et al., 2015
pd1Tg/+		7 figures from 4 publications	14 figures from 6 publications
pd1Tg/+ (AB)		4 figures from 2 publications	6 figures from 2 publications
pd1Tg/+ (EKW)
pd1Tg/+ + MO2-dld (AB)		Fig. 5 from Lee et al., 2014	Fig. 5 from Lee et al., 2014
pd1Tg/pd1Tg		Fig. 2 from Keskin et al., 2019	2 figures from 2 publications
pd1Tg/pd1Tg; zf106Tg/zf106Tg		Fig. 2 from Klingbeil et al., 2021	Fig. 2 from Klingbeil et al., 2021
pd1Tg; s896Tg		Fig. 7 from Liu et al., 2013	Fig. 7 from Liu et al., 2013
pd1Tg; umk701Tg
pd1Tg; wprt8Tg		Fig. 5 from Blitz et al., 2021	Fig. 5 from Blitz et al., 2021
pd1Tg; zf106Tg		Fig. 1 from Neelathi et al., 2018	Fig. 1 from Neelathi et al., 2018

Sequence Information

Other Construct Pages

None

Citations