ZFIN ID: ZDB-GENE-050622-14
Gene Name: ETS1-related protein
Gene Symbol: etsrp    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: ets1b, etsrp71 (1), etsrp (2), etv2, er71 (1), ETS1-related protein (1), v-ets erythroblastosis virus E26 oncogene homolog 1b, wu:fc49b07, zgc:153819

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including adrenal gland development; circulatory system development; and hemopoiesis. Predicted to localize to the nucleus. Is expressed in several structures, including cardiovascular system; head mesenchyme; hematopoietic system; mesoderm; and pharyngeal arch 3-7. Orthologous to human ETV2 (ETS variant transcription factor 2).
Genome Resources: Alliance (1),  Gene:555766 (1),  Ensembl(GRCz11):ENSDARG00000053868 (2)
GENE EXPRESSION
All Expression Data: 91 figures from 47 publications
Directly Submitted Expression Data: 11 figures (33 images) from Rauch et al., 2003 [fc49b07]
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
y11 Insertion Unknown Unknown ENU
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-etsrp
3
MO1-etsrp N/A 22
MO2-etsrp N/A 32
MO3-etsrp N/A 4
MO4-etsrp N/A 2
MO5-etsrp N/A 2
DISEASE ASSOCIATED WITH etsrp HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH etsrp VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process positive regulation of transcription by RNA polymerase II (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 24)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR000418 Ets domain
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA etv2-201 (1)    Ensembl 1453
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-etv2 polyclonal Rabbit IHC Kerafast
3
CONSTRUCTS WITH SEQUENCES FROM etsrp
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(-.6etsrp:etsrp-EGFP) etsrp EGFPetsrp Danio rerio 1 4
Tg(-2.2etsrp:etsrp-EGFP) etsrp EGFPetsrp Danio rerio 1 3
Tg(-2.2etsrp:Kaede) etsrp Kaede Danio rerio 1 3
Tg(-2.3etsrp:etsrp-EGFP) etsrp EGFPetsrp Danio rerio 1 4
Tg(-3.1etsrp:etsrp-EGFP) etsrp EGFPetsrp Danio rerio 1 4
Tg(-4.2etsrp:etsrp-mCherry) etsrp etsrpmCherry Danio rerio 1 3
Tg(etsrp:Cre) etsrp Cre Danio rerio 1 1
Tg(hsp70l:etsrp-NLS-mCherry) hsp70l etsrpmCherry Danio rerio 1 2
Tg1(etsrp-gata2a:EGFP) etsrpgata2a EGFP Danio rerio 1 2
Tg1(etsrp:EGFP) etsrp EGFP Danio rerio 1 4
Tg1(etsrp:mCherry) etsrp mCherry Danio rerio 1 3
Tg2(etsrp-gata2a:EGFP) etsrpgata2a EGFP Danio rerio 1 2
Tg2(etsrp:EGFP) etsrp EGFP Danio rerio 1 2
Tg2(etsrp:mCherry) etsrp mCherry Danio rerio 1 2
Tg3(etsrp:EGFP) etsrp EGFP Danio rerio 1 2
Tg3(etsrp:mCherry) etsrp mCherry Danio rerio 1 2
TgBAC(etsrp:EGFP) etsrp EGFP Danio rerio 4 27
TgBAC(etsrp:Kaede) etsrp Kaede Danio rerio 1 7
MARKER RELATIONSHIPS
etsrp Contained in: [BAC] CH211-225P5 (1)
etsrp Encodes: [EST] fc49b07 (1) (order this)
[cDNA] MGC:153819 (1), MGC:191940 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001037375 (1) 1478 nt
Genomic GenBank:BX649388 (1) 177865 nt
Select Tool
Polypeptide UniProtKB:Q30JB6 (1) 366 aa
Sequence Information (all 23)
ORTHOLOGY for etsrp ( Chr: 16 )
CITATIONS (147)