ZFIN ID: ZDB-FISH-150901-25651
Fish name: pd1Tg
Genotype: pd1Tg
Targeting Reagent: none
HUMAN DISEASE MODELED by pd1Tg
No data available
GENE EXPRESSION
Gene expression in pd1Tg
RNA expression
Expressed Gene Structure Conditions Figures
and2 heat shock, amputation: caudal fin Fig. 8 with image from König et al., 2017
atoh1a standard conditions Fig. 6 with image from Su et al., 2014
heat shock Fig. 2 from Wang et al., 2015
atoh1c heat shock Fig. 3 with image from Kidwell et al., 2018
bmp4 heat shock Fig. 4 from Pouget et al., 2014
dusp6 physical alteration: anatomical structure Fig. 6 with image from Lee et al., 2005
en2a standard conditions Fig. 4 with image from Nguyen-Chi et al., 2012
heat shock Fig. 4 with image from Nguyen-Chi et al., 2012
etv4 heat shock Fig. 1 from Pouget et al., 2014
etv5b heat shock Fig. 3 with image from Vemaraju et al., 2012
fgf1a heat shock Fig. 2 from Schall et al., 2017
foxd5 heat shock Fig. 5 with image from Lee et al., 2009
gata3 physical alteration: anatomical structure, heat shock Fig. 4 with image from Kizil et al., 2012
grem1a heat shock Fig. 4 from Pouget et al., 2014
gsc heat shock Fig. 1 with image from Kantarci et al., 2016
id1 heat shock Fig. 5 from Pouget et al., 2014
lamb1a heat shock, amputation: caudal fin Fig. 7 with image from Chen et al., 2015
mespaa heat shock Fig. 7 with image from Lee et al., 2009
mespba heat shock Fig. 7 with image from Lee et al., 2009
myb heat shock Fig. 1 from Pouget et al., 2014
nav3 heat shock Fig. 5 with image from Klein et al., 2011
neurod1 heat shock Fig. 7 with imageFig. 8 with image from Kantarci et al., 2015
Fig. 8 with image from Vemaraju et al., 2012
neurog1 heat shock Fig. 6 with imageFig. 7 with image from Kantarci et al., 2015
Fig. 4 with image from Vemaraju et al., 2012
nog2 heat shock Fig. 4 from Pouget et al., 2014
pax2a standard conditions Fig. 6 with image from Su et al., 2014
prl heat shock Fig. 7 with image from Liu et al., 2013
rag1 heat shock Fig. 1 from Pouget et al., 2014
runx1 heat shock Fig. 1Fig. 3Fig. 5Fig. 6 from Pouget et al., 2014
shroom3 standard conditions Fig. 6 with image from Ernst et al., 2012
heat shock Fig. 6 with image from Ernst et al., 2012
sox9a heat shock Fig. 2 from Wang et al., 2015
spry4 heat shock Fig. 4 with image from Kizil et al., 2012
tbx18 heat shock Fig. 6 with image from Wills et al., 2008
tbx20 heat shock Fig. 3 from Pouget et al., 2014
vsx2 control Fig. 6 with image from Wong et al., 2015
heat shock Fig. 6 with image from Wong et al., 2015
Protein expression
Antibody Antigen Genes Structure Conditions Figures
Ab2-and1 heat shock, amputation: caudal fin Fig. 8 with image from König et al., 2017
Ab1-map1lc3 resection: lateral rectus, heat shock Fig. 7 with image from Saera-Vila et al., 2016
Ab-F59 heat shock Fig. 4 with image from Nguyen-Chi et al., 2012
Ab1-elavl heat shock Fig. 1 from Wang et al., 2015
zn-5 control Fig. 6 with image from Wong et al., 2015
Ab-2F11 heat shock Fig. 1 with image from Liu et al., 2013
Ab1-tuba heat shock Fig. 7 with image from Liu et al., 2013
Ab10-mapk control Fig. 2 from Schall et al., 2017
Ab-F59 standard conditions Fig. 4 with image from Nguyen-Chi et al., 2012
Ab10-mapk heat shock Fig. 2 from Schall et al., 2017
Ab6-sqstm1 resection: lateral rectus, heat shock Fig. 7 with image from Saera-Vila et al., 2016
Ab2-isl heat shock Fig. 7 with imageFig. 8 with image from Kantarci et al., 2015
Fig. 8 with image from Vemaraju et al., 2012
zn-5 heat shock Fig. 6 with image from Wong et al., 2015
Reporter gene expression
Expressed Gene Structure Conditions Figures
EGFP standard conditions Fig. 4 with image from Nguyen-Chi et al., 2012
heat shock Fig. 6 with image from Richardson et al., 2016
Fig. 7 with image from Saera-Vila et al., 2016
Fig. 4 with image from Kizil et al., 2012
Fig. 4 with image from Nguyen-Chi et al., 2012
Fig. 1 from Diep et al., 2011
PHENOTYPE
Phenotype in pd1Tg
Phenotype Conditions Figures
autophagy occurrence, ameliorated resection: lateral rectus, heat shock Fig. 7 with image from Saera-Vila et al., 2016
axial vasculature id1 expression increased amount, abnormal heat shock Fig. 5 from Pouget et al., 2014
axial vasculature anatomical region id1 expression mislocalised, abnormal heat shock Fig. 5 from Pouget et al., 2014
cardiac muscle tissue regeneration decreased process quality, abnormal cold damage: heart, heat shock Fig. 4 with imageFig. 5 with image from Koth et al., 2017
cardiac muscle tissue regeneration decreased process quality, abnormal resection: heart, heat shock Fig. 5 with image from Koth et al., 2017
caudal fin etv4 expression decreased amount, abnormal heat shock Fig. 1 from Pouget et al., 2014
dorsal aorta runx1 expression increased amount, abnormal heat shock Fig. 1Fig. 3Fig. 5 from Pouget et al., 2014
dorsal aorta myb expression increased amount, abnormal heat shock Fig. 1 from Pouget et al., 2014
dorsal aorta runx1 expression increased distribution, abnormal heat shock Fig. 3Fig. 5 from Pouget et al., 2014
dorsal aorta runx1 expression mislocalised, abnormal heat shock Fig. 3Fig. 5 from Pouget et al., 2014
dorsal aorta anatomical region bmp4 expression increased amount, abnormal heat shock Fig. 4 from Pouget et al., 2014
embryonic retina morphogenesis in camera-type eye decreased process quality, abnormal heat shock Fig. 4 with image from Picker et al., 2009
eye decreased size, abnormal heat shock Fig. 6 with image from Wong et al., 2015
fin regeneration decreased efficacy, abnormal heat shock, amputation: caudal fin Fig. 8 with image from König et al., 2017
goblet cell increased amount, abnormal resection: intestine Fig. 5 from Schall et al., 2017
goblet cell increased amount, ameliorated resection: intestine, heat shock Fig. 5 from Schall et al., 2017
head etv4 expression decreased amount, abnormal heat shock Fig. 1 from Pouget et al., 2014
hematopoietic stem cell increased amount, abnormal heat shock Fig. 1 from Pouget et al., 2014
hematopoietic system myb expression increased amount, abnormal heat shock Fig. 1 from Pouget et al., 2014
intervillus pockets decreased amount, abnormal resection: intestine, heat shock Fig. 3 from Schall et al., 2017
intervillus pockets ab10-mapk labeling increased amount, abnormal resection: intestine Fig. 2 from Schall et al., 2017
intervillus pockets cytoplasm ab10-mapk labeling decreased amount, abnormal heat shock Fig. 2 from Schall et al., 2017
intestinal villus perimeter, ameliorated resection: intestine, heat shock Fig. 3 from Schall et al., 2017
intestinal villus perimeter, ameliorated resection: intestine Fig. 3 from Schall et al., 2017
intestinal villus cell population proliferation increased occurrence, abnormal resection: intestine Fig. 4 from Schall et al., 2017
intestinal villus cell population proliferation increased occurrence, abnormal resection: intestine, heat shock Fig. 4 from Schall et al., 2017
intestinal villus mesenchyme ab10-mapk labeling mislocalised, abnormal resection: intestine Fig. 2 from Schall et al., 2017
intestinal villus mesenchyme ab10-mapk labeling mislocalised, abnormal resection: intestine, heat shock Fig. 2 from Schall et al., 2017
intestine fgf1a expression decreased amount, abnormal resection: intestine, heat shock Fig. 2 from Schall et al., 2017
intestine fgf1a expression decreased amount, abnormal heat shock Fig. 2 from Schall et al., 2017
intestine has fewer parts of type enteroendocrine cell, abnormal heat shock Fig. 1 with image from Liu et al., 2013
intestine has fewer parts of type goblet cell, abnormal heat shock Fig. 1 with image from Liu et al., 2013
lateral rectus regenerating tissue ab1-map1lc3 labeling amount, ameliorated resection: lateral rectus, heat shock Fig. 7 with image from Saera-Vila et al., 2016
lateral rectus regenerating tissue Ab6-sqstm1 labeling increased amount, abnormal resection: lateral rectus, heat shock Fig. 7 with image from Saera-Vila et al., 2016
midbrain hindbrain boundary atoh1c expression absent, abnormal heat shock Fig. 3 with image from Kidwell et al., 2018
migratory slow muscle precursor cell malformed, abnormal heat shock Fig. 4 with image from Nguyen-Chi et al., 2012
Muller cell cell population proliferation decreased process quality, abnormal perforation: retina, heat shock Fig. 2 with image from Wan et al., 2014
muscle pioneer increased amount, abnormal heat shock Fig. 4 with image from Nguyen-Chi et al., 2012
neurohypophysis innervation decreased occurrence, abnormal heat shock Fig. 7 with image from Liu et al., 2013
neurohypophysis innervation decreased occurrence, abnormal heat shock Fig. 7 with image from Liu et al., 2013
neuromast hair cell decreased amount, abnormal heat shock, chemical treatment by environment: neomycin Fig. 4 with image from Lee et al., 2016
optic vesicle malformed, abnormal heat shock Fig. 4 with image from Picker et al., 2009
otic vesicle has extra parts of type otic vesicle neuroblast (sensu Vertebrata), abnormal heat shock, chemical treatment: LY-411575 Fig. 7 with image from Kantarci et al., 2015
otic vesicle has extra parts of type otic vesicle neuroblast (sensu Vertebrata), abnormal heat shock Fig. 7 with image from Kantarci et al., 2015
otic vesicle fibroblast growth factor receptor signaling pathway decreased process quality, abnormal heat shock, chemical treatment: LY-411575 Fig. 7 with image from Kantarci et al., 2015
otic vesicle fibroblast growth factor receptor signaling pathway decreased process quality, abnormal heat shock Fig. 7 with image from Kantarci et al., 2015
otic vesicle neuroblast fate specification increased occurrence, abnormal heat shock, chemical treatment: LY-411575 Fig. 7 with image from Kantarci et al., 2015
otic vesicle neuroblast fate specification occurrence, normal heat shock Fig. 6 with imageFig. 7 with image from Kantarci et al., 2015
otic vesicle Notch signaling pathway decreased process quality, abnormal heat shock, chemical treatment: LY-411575 Fig. 7 with image from Kantarci et al., 2015
otic vesicle ventro-lateral region gsc expression absent, abnormal heat shock Fig. 1 with image from Kantarci et al., 2016
regenerating fin and2 expression decreased amount, abnormal heat shock, amputation: caudal fin Fig. 8 with image from König et al., 2017
regenerating fin lamb1a expression decreased amount, abnormal heat shock, amputation: caudal fin Fig. 7 with image from Chen et al., 2015
regenerating fin ab2-and1 labeling decreased amount, abnormal heat shock, amputation: caudal fin Fig. 8 with image from König et al., 2017
regenerating fin caudal fin actinotrichium ab2-and1 labeling decreased amount, abnormal heat shock, amputation: caudal fin Fig. 8 with image from König et al., 2017
regenerating tissue autophagy occurrence, ameliorated resection: lateral rectus, heat shock Fig. 7 with image from Saera-Vila et al., 2016
regenerating tissue Muller cell decreased amount, abnormal perforation: retina, heat shock Fig. 2 with image from Wan et al., 2014
retina central region vsx2 expression decreased amount, abnormal heat shock Fig. 6 with image from Wong et al., 2015
retina tissue regeneration process quality, abnormal perforation: retina, heat shock Fig. 2 with image from Wan et al., 2014
sclerotome nog2 expression decreased amount, abnormal heat shock Fig. 4 from Pouget et al., 2014
sclerotome grem1a expression decreased amount, abnormal heat shock Fig. 4 from Pouget et al., 2014
statoacoustic (VIII) ganglion has extra parts of type statoacoustic (VIII) ganglion neuron, abnormal heat shock Fig. 7 with image from Kantarci et al., 2015
statoacoustic (VIII) ganglion has extra parts of type statoacoustic (VIII) ganglion neuron, abnormal heat shock, chemical treatment: LY-411575 Fig. 8 with image from Kantarci et al., 2015
statoacoustic (VIII) ganglion has fewer parts of type statoacoustic (VIII) ganglion neuron, abnormal heat shock, chemical treatment: LY-411575 Fig. 7 with image from Kantarci et al., 2015
statoacoustic (VIII) ganglion has fewer parts of type statoacoustic (VIII) ganglion neuroblast (sensu Vertebrata), abnormal heat shock, chemical treatment: LY-411575 Fig. 7 with imageFig. 8 with image from Kantarci et al., 2015
statoacoustic (VIII) ganglion has fewer parts of type statoacoustic (VIII) ganglion neuroblast (sensu Vertebrata), abnormal heat shock Fig. 7 with image from Kantarci et al., 2015
statoacoustic (VIII) ganglion anatomical region decreased size, abnormal heat shock Fig. 1 from Wang et al., 2015
statoacoustic (VIII) ganglion neuroblast proliferation occurrence, normal heat shock, chemical treatment: LY-411575 Fig. 8 with image from Kantarci et al., 2015
thymus T cell decreased amount, abnormal heat shock Fig. 1 from Pouget et al., 2014
thymus T cell rag1 expression increased amount, abnormal heat shock Fig. 1 from Pouget et al., 2014
trunk etv4 expression decreased amount, abnormal heat shock Fig. 1 from Pouget et al., 2014
trunk runx1 expression increased amount, abnormal heat shock Fig. 1 from Pouget et al., 2014
trunk rag1 expression increased amount, abnormal heat shock Fig. 1 from Pouget et al., 2014
trunk mesenchyme bmp4 expression increased amount, abnormal heat shock Fig. 4 from Pouget et al., 2014
trunk mesenchyme bmp4 expression increased distribution, abnormal heat shock Fig. 4 from Pouget et al., 2014
ventral wall of dorsal aorta runx1 expression increased amount, abnormal heat shock Fig. 1Fig. 6 from Pouget et al., 2014
ventral wall of dorsal aorta runx1 expression increased distribution, abnormal heat shock Fig. 3Fig. 5Fig. 6 from Pouget et al., 2014
ventricular epicardium decreased size, abnormal heat shock Fig. 6 with image from Wills et al., 2008
whole organism decreased weight, abnormal heat shock Fig. 3 from Schall et al., 2017
whole organism decreased weight, abnormal resection: intestine Fig. 3 from Schall et al., 2017
whole organism decreased weight, exacerbated resection: intestine, heat shock Fig. 3 from Schall et al., 2017

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