ZFIN ID: ZDB-GENE-040426-1275
Gene Name: forkhead box M1
Gene Symbol: foxm1    Nomenclature History

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Previous Names: foxm1l (1), zgc:63854 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and protein kinase binding activity. Predicted to be involved in several processes, including DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; regulation of nucleobase-containing compound metabolic process; and vasculogenesis. Predicted to localize to nucleus. Orthologous to human FOXM1 (forkhead box M1).
Genome Resources: Alliance (1),  Gene:394072 (1),  Ensembl(GRCz11):ENSDARG00000003200 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:63854]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la015505Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10708 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40220 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-foxm1 N/A 2
    DISEASE ASSOCIATED WITH foxm1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH foxm1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process G2/M transition of mitotic cell cycle (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA foxm1-201 (1)    Ensembl 3385
    foxm1-203 (1)    Ensembl 695
    foxm1-204 (1)    Ensembl 745
    ncRNA foxm1-005 (1)    Ensembl 742
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM foxm1 No data available
    MARKER RELATIONSHIPS
    foxm1 Contained in: [BAC] CH73-352P4 (1)
    foxm1 Encodes: [cDNA] MGC:63854 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201097 (1) 3396 nt
    Genomic GenBank:CU571169 (1) 104729 nt
    Select Tool
    Polypeptide UniProtKB:F1QRF9 (1) 623 aa
    Sequence Information (all 16)
    ORTHOLOGY for foxm1 ( Chr: 4 )
    CITATIONS (28)