ZFIN ID: ZDB-FIG-190827-26 |
Park et al., 2019
- Low dose of chronic ethanol exposure in adult zebrafish induces hepatic steatosis and injury.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
117:109179
Full text @ Biomed. Pharmacother.
EXPRESSION / LABELING:
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Anatomical Term: | |
Stage: | Adult |
PHENOTYPE:
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Observed In: | |
Stage: | Adult |
Fig. 2 Chronic ethanol treatment induced steatosis in the liver of adult zebrafish. (A) The relative mRNA expression of genes associated with lipid metabolism include lipogenic transcription factors, lipid synthesis, lipid uptake, and fatty acid transporting into the mitochondria. (B) Oil red O staining the section of liver in untreated control (left) and 0.2% ethanol treated wild type zebrafish. Scale bar = 50 μm. (C) The quantification of triglycerides in the liver of control and ethanol treated zebrafish. Error bars indicate standard deviation of the mean. * p < 0.05, ** p < 0.005. |
Gene Expression Details
Gene | Antibody | Fish | Conditions | Stage | Anatomy | Assay |
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cebpa | WT | chemical treatment by environment: ethanol | Adult | liver | RTPCR | |
dffa | WT | chemical treatment by environment: ethanol | Adult | liver | RTPCR | |
dgat2 | WT | chemical treatment by environment: ethanol | Adult | liver | RTPCR | |
fasn | WT | chemical treatment by environment: ethanol | Adult | liver | RTPCR | |
ldlra | WT | chemical treatment by environment: ethanol | Adult | liver | RTPCR | |
lpl | WT | chemical treatment by environment: ethanol | Adult | liver | RTPCR | |
srebf1 | WT | chemical treatment by environment: ethanol | Adult | liver | RTPCR | |
srebf2 | WT | chemical treatment by environment: ethanol | Adult | liver | RTPCR |
Antibody Labeling Details
No data available
Phenotype Details
Acknowledgments: | ZFIN wishes to thank the journal Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Biomed. Pharmacother. |
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