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General Information
ZIRC
ZFIN ID: ZDB-GENE-090812-3
Gene Name: sterol regulatory element binding transcription factor 1
Gene Symbol: srebf1
Sequence Ontology ID : SO:0000704

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Previous Name: SREBP1 (1)

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(Including Attributions)
Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in liver development; pancreas regeneration; and  ...
GENE EXPRESSION
All Expression Data: 23 figures from 21 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa18770 Point Mutation Unknown Premature Stop ENU
sa33346 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 3 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH srebf1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH srebf1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process liver development (more)
    Molecular Function protein dimerization activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR011598 (1)
  • InterPro:IPR036638 (1)
  • PROSITE:PS50888 (1)
  • Pfam:PF00010 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM srebf1 No data available
    MARKER RELATIONSHIPS
    srebf1Contains: [SSLP] z1191
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001105129 (1) 3504bp
    Genomic GenBank:DQ836066 (1) 3143bp
    Polypeptide UniProtKB:A6XLD8 (1) 1105aa
    Sequence Clusters UniGene:78402 (1)
    Sequence Information (all 14)
    OTHER srebf1 GENE PAGES
  • Alliance (1)
  • Gene:793274 (1)
  • Ensembl(GRCz11):ENSDARG00000067607 (2)
  • ORTHOLOGY for srebf1 (Chr: 3)
    CITATIONS (75)