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General Information
ZIRC
ZFIN ID: ZDB-GENE-070410-8
Gene Name: sterol regulatory element binding transcription factor 2
Gene Symbol: srebf2
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:158371

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(Including Attributions)
Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in liver development. Predicted to localize to the  ...
GENE EXPRESSION
All Expression Data: 12 figures from 10 publications
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6024 Point Mutation Unknown Splice Site ENU
sa19922 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31309 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44553 Point Mutation Unknown Unknown ENU
    Targeting reagents:
    PHENOTYPE
    Data: Fig. S7 from Liu et al., 2016
    Observed in:
    DISEASE ASSOCIATED WITH srebf2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH srebf2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process liver development (more)
    Cellular Component cytoplasmic vesicle (more)
    Molecular Function DNA binding (more)
    GO Terms (all 20)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR011598 (1)
  • InterPro:IPR036638 (1)
  • PROSITE:PS50888 (1)
  • Pfam:PF00010 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA srebf2-201 (1) 4383
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM srebf2 No data available
    MARKER RELATIONSHIPS
    srebf2Contained in: [BAC] CH73-211L13 (1) (order this)
    [Fosmid] CH1073-322P19 (1) (order this)
    srebf2Encodes: [cDNA] MGC:158371 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001089466 (1) 4496bp
    Genomic GenBank:CU672266 (1) 104622bp
    Select Tool
    Polypeptide UniProtKB:A3KNA7 (1) 1099aa
    Sequence Clusters UniGene:82297 (1)
    Sequence Information (all 13)
    ORTHOLOGY for srebf2 (Chr: 3)
    CITATIONS (47)