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ZIRC
ZFIN ID: ZDB-FIG-190712-24
Moore et al., 2018 - Gfi1aa and Gfi1b set the pace for primitive erythroblast differentiation from hemangioblasts in the zebrafish embryo. Blood advances   2:2589-2606 Full text @ Blood Adv
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage Range: 5-9 somites to 20-25 somites
PHENOTYPE:
Fish:
Observed In:
Stage Range: 10-13 somites to Adult

Fig. 7 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
etsrp gfi1aaqmc551Gt/qmc551Gt ; gfi1bqmc554/qmc554 standard conditions 20-25 somites erythroblast RTPCR
hbbe1.1 gfi1aaqmc551Gt/qmc551Gt ; gfi1bqmc554/qmc554 standard conditions 10-13 somites Not Detected endothelial cell ISH
gfi1bqmc554/qmc554 ; gfi1aaqmc551Gt/+ standard conditions 10-13 somites erythroblast ISH
myod1 WT standard conditions 5-9 somites adaxial cell ISH
5-9 somites somite ISH
gfi1aaqmc551Gt/qmc551Gt ; gfi1bqmc554/qmc554 standard conditions 5-9 somites adaxial cell ISH
5-9 somites somite ISH
nkx2.5 WT standard conditions 5-9 somites heart primordium ISH
gfi1aaqmc551Gt/qmc551Gt ; gfi1bqmc554/qmc554 standard conditions 5-9 somites heart primordium ISH
npas4l WT standard conditions 5-9 somites posterior lateral mesoderm ISH
gfi1aaqmc551Gt/qmc551Gt ; gfi1bqmc554/qmc554 standard conditions 5-9 somites posterior lateral mesoderm ISH
10-13 somites posterior lateral mesoderm ISH
gfi1bqmc554/qmc554 ; gfi1aaqmc551Gt/+ standard conditions 10-13 somites posterior lateral mesoderm ISH
pax2a WT standard conditions 5-9 somites pronephric mesoderm ISH
gfi1aaqmc551Gt/qmc551Gt ; gfi1bqmc554/qmc554 standard conditions 5-9 somites pronephric mesoderm ISH
slc4a1a gfi1aaqmc551Gt/qmc551Gt ; gfi1bqmc554/qmc554 standard conditions 20-25 somites erythroblast RTPCR
zfp36l2 gfi1aaqmc551Gt/qmc551Gt ; gfi1bqmc554/qmc554 standard conditions 20-25 somites erythroblast RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
gfi1aaqmc551Gt/qmc551Gt standard conditions Adult erythroblast increased amount, abnormal
Adult nucleate erythrocyte morphology, abnormal
gfi1aaqmc551Gt/qmc551Gt ; gfi1bqmc554/qmc554 standard conditions 10-13 somites endothelial cell hbbe1.1 expression absent, abnormal
20-25 somites erythroblast slc4a1a expression decreased amount, abnormal
20-25 somites erythroblast etsrp expression increased amount, abnormal
20-25 somites erythroblast zfp36l2 expression increased amount, abnormal
Adult erythroblast increased amount, abnormal
Adult nucleate erythrocyte morphology, abnormal
Adult nucleate erythrocyte nucleus morphology, abnormal
gfi1bqmc554/+ ; gfi1aaqmc551Gt/qmc551Gt standard conditions Adult erythroblast increased amount, abnormal
Adult nucleate erythrocyte morphology, abnormal
Full text @ Blood Adv